AIMC Topic: Glucosephosphate Dehydrogenase

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Discovery of Small-Molecule Activators for Glucose-6-Phosphate Dehydrogenase (G6PD) Using Machine Learning Approaches.

International journal of molecular sciences Feb 23, 2020
Glucose-6-Phosphate Dehydrogenase (G6PD) is a ubiquitous cytoplasmic enzyme converting glucose-6-phosphate into 6-phosphogluconate in the pentose phosphate pathway (PPP). The G6PD deficiency renders the inability to regenerate glutathione due to lack...
Humans Machine Learning Animals Molecular Docking Simulation Drug Discovery Oxidative Stress Oxidation-Reduction Glucosephosphate Dehydrogenase Deficiency Drug Evaluation, Preclinical Catalytic Domain Glutathione X-Ray Diffraction Protein Interaction Domains and Motifs Glucosephosphate Dehydrogenase NADP Pentose Phosphate Pathway
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Data mining and pathway analysis of glucose-6-phosphate dehydrogenase with natural language processing.

Molecular medicine reports Jun 15, 2017
Human glucose-6-phosphate dehydrogenase (G6PD) is a crucial enzyme in the pentose phosphate pathway, and serves an important role in biosynthesis and the redox balance. G6PD deficiency is a major cause of neonatal jaundice and acute hemolyticanemia, ...
Humans Gene Regulatory Networks Signal Transduction MicroRNAs Natural Language Processing Metabolic Networks and Pathways Glucosephosphate Dehydrogenase Deficiency Data Mining Gene Ontology Glucosephosphate Dehydrogenase
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