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Glucosephosphate Dehydrogenase

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Data mining and pathway analysis of glucose-6-phosphate dehydrogenase with natural language processing.

Molecular medicine reports 28627690
Human glucose-6-phosphate dehydrogenase (G6PD) is a crucial enzyme in the pentose phosphate pathway, and serves an important role in biosynthesis and the redox balance. G6PD deficiency is a major cause of neonatal jaundice and acute hemolyticanemia, ...
Data Mining Gene Ontology Gene Regulatory Networks Glucosephosphate Dehydrogenase Glucosephosphate Dehydrogenase Deficiency Humans Metabolic Networks and Pathways MicroRNAs Natural Language Processing Signal Transduction
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Discovery of Small-Molecule Activators for Glucose-6-Phosphate Dehydrogenase (G6PD) Using Machine Learning Approaches.

International journal of molecular sciences 32102234
Glucose-6-Phosphate Dehydrogenase (G6PD) is a ubiquitous cytoplasmic enzyme converting glucose-6-phosphate into 6-phosphogluconate in the pentose phosphate pathway (PPP). The G6PD deficiency renders the inability to regenerate glutathione due to lack...
Animals Catalytic Domain Drug Discovery Drug Evaluation, Preclinical Glucosephosphate Dehydrogenase Glucosephosphate Dehydrogenase Deficiency Glutathione Humans Machine Learning Molecular Docking Simulation NADP Oxidation-Reduction Oxidative Stress Pentose Phosphate Pathway Protein Interaction Domains and Motifs X-Ray Diffraction
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