AIMC Topic: Glucosephosphate Dehydrogenase Deficiency
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Glucose-6-phosphate dehydrogenase deficiency with coinherited Gaucher disease: A rare association.
Indian journal of pathology & microbiology
Jul 6, 2023
Anemia coexisting with Gaucher disease (GD) is often associated with non-hemolytic processes. Few cases of GD with autoimmune hemolytic anemia have been reported. However, literature on GD with concomitant nonimmune hemolytic anemia is scarce. A 1-ye...
Discovery of Small-Molecule Activators for Glucose-6-Phosphate Dehydrogenase (G6PD) Using Machine Learning Approaches.
International journal of molecular sciences
Feb 23, 2020
Glucose-6-Phosphate Dehydrogenase (G6PD) is a ubiquitous cytoplasmic enzyme converting glucose-6-phosphate into 6-phosphogluconate in the pentose phosphate pathway (PPP). The G6PD deficiency renders the inability to regenerate glutathione due to lack...
Machine Learning
Animals
Humans
Glutathione
X-Ray Diffraction
Catalytic Domain
NADP
Oxidation-Reduction
Glucosephosphate Dehydrogenase
Pentose Phosphate Pathway
Protein Interaction Domains and Motifs
Drug Evaluation, Preclinical
Glucosephosphate Dehydrogenase Deficiency
Molecular Docking Simulation
Drug Discovery
Oxidative Stress
[Hemoglobinuria in children hospitalized in Ouagadougou: short term inpatient care and prognosis].
The Pan African medical journal
Nov 26, 2019
INTRODUCTION: The purpose of this study was to analyze the epidemiological, diagnostic, therapeutic and evolutionary features of hemoglobinuria in children hospitalized in the Pediatric University Hospital Charles de Gaulle, Ouagadougou.
Data mining and pathway analysis of glucose-6-phosphate dehydrogenase with natural language processing.
Molecular medicine reports
Jun 15, 2017
Human glucose-6-phosphate dehydrogenase (G6PD) is a crucial enzyme in the pentose phosphate pathway, and serves an important role in biosynthesis and the redox balance. G6PD deficiency is a major cause of neonatal jaundice and acute hemolyticanemia, ...
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