Dementia typically results from damage to neural pathways and the consequent degeneration of neuronal connections. Graph neural networks (GNNs) have been widely employed to model complex brain networks. However, leveraging the complementary temporal,...
This paper presents a novel framework for detecting and predicting abnormal traffic events on highways. Current traffic monitoring systems often rely on single data sources, which limits their detection accuracy and robustness in complex environments...
Journal of chemical information and modeling
Jun 5, 2025
The forecasting of drug-target interactions (DTIs) is a crucial element in the domain of drug repositioning. Current methodologies, primarily based on dual-branch architectures or graph neural networks (GNNs), typically model binary associations─spec...
Alzheimer's disease (AD) is a prevalent neurodegenerative disease that primarily affects the elderly population. The early detection of mild cognitive impairment (MCI) holds significant clinical importance for prompt intervention and treatment of AD....
IEEE journal of biomedical and health informatics
May 6, 2025
The multi-modal neuroimage study has provided insights into understanding the heteromodal relationships between brain network organization and behavioral phenotypes. Integrating data from various modalities facilitates the characterization of the int...
IEEE transactions on neural networks and learning systems
May 2, 2025
Due to the absence of a gold standard for threshold selection, brain networks constructed with inappropriate thresholds risk topological degradation or contain noise connections. Therefore, graph neural networks (GNNs) exhibit weak robustness and ove...
IEEE transactions on neural networks and learning systems
May 2, 2025
Reconstructing gene regulatory networks (GRNs) using single-cell RNA sequencing (scRNA-seq) data holds great promise for unraveling cellular fate development and heterogeneity. While numerous machine-learning methods have been proposed to infer GRNs ...
The CRISPR-Cas system, an adaptive immune mechanism found in bacteria and archaea, has evolved into a promising genomic editing tool, with various types of Cas proteins playing a crucial role. In this study, we developed a set of strategies for minin...
Anesthesia plays a pivotal role in modern surgery by facilitating controlled states of unconsciousness. Precise control is crucial for safe and pain-free surgeries. Monitoring anesthesia depth accurately is essential to guide anesthesiologists, optim...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Apr 16, 2025
The coordination of muscles in human locomotion is commonly understood as the integration of motor modules known as muscle synergies. Recent research has delved into the adaptation of muscle synergies during the acquisition of new motor skills. Howev...
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