Mild to severe anemia is caused by thalassemia, a common genetic disorder affecting over 100 countries worldwide, that results from the abnormality of one or several of the four globin genes. This leads to chronic hemolytic anemia and disrupted synth...
PURPOSE: Machine learning is a powerful tool to develop algorithms for clinical diagnosis. However, standard machine learning algorithms are not perfectly suited for clinical data since the data are interconnected and may contain time series. As show...
BACKGROUND: To compare the demographic characteristics, maternal and perinatal outcomes and hemoglobin parameters according to stages diagnosed with placental abruption.
BMC medical informatics and decision making
Jun 4, 2025
The detection and classification of blood cells are important in diagnosing and monitoring a variety of blood-related illnesses, such as anemia, leukemia, and infection, all of which may cause significant mortality. Accurate blood cell identification...
INTRODUCTION: Sepsis is a life-threatening condition characterized by widespread inflammatory response syndrome in the body resulting from infection. Previous studies have demonstrated that some inflammatory factors or nutritional elements contribute...
BACKGROUND: Sepsis is an organ dysfunction caused by a dysregulated host response to infection. Early detection is fundamental to improving the patient outcome. Laboratory medicine can play a crucial role by providing biomarkers whose alteration can ...
BACKGROUND: Sepsis, a critical global health challenge, accounted for approximately 20% of worldwide deaths in 2017. Although the Sequential Organ Failure Assessment (SOFA) score standardizes the diagnosis of organ dysfunction, early sepsis detection...
Computer methods and programs in biomedicine
Jan 6, 2025
BACKGROUND: Around 7% of the global population has congenital hemoglobin disorders, with over 300,000 new cases of α-thalassemia annually. Diagnosis is costly and inaccurate in low-income regions, often relying on complete blood count (CBC) tests. Th...
INTRODUCTION: Elevated levels of low-density lipoprotein-cholesterol (LDL-C) is a significant risk factor for the development of cardiovascular diseases (CVD)s. Furthermore, studies have revealed an association between indices of the complete blood c...
Optimizing early breast cancer (BC) detection requires effective risk assessment tools. This retrospective study from Brazil showcases the efficacy of machine learning in discerning complex patterns within routine blood tests, presenting a globally a...
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