AIMC Topic: Haplorhini

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A neural network that finds a naturalistic solution for the production of muscle activity.

Nature neuroscience
It remains an open question how neural responses in motor cortex relate to movement. We explored the hypothesis that motor cortex reflects dynamics appropriate for generating temporally patterned outgoing commands. To formalize this hypothesis, we tr...

Speed-accuracy tradeoff by a control signal with balanced excitation and inhibition.

Journal of neurophysiology
A hallmark of flexible behavior is the brain's ability to dynamically adjust speed and accuracy in decision-making. Recent studies suggested that such adjustments modulate not only the decision threshold, but also the rate of evidence accumulation. H...

Robot Assisted Neurosurgery for High-Accuracy, Minimally-Invasive Deep Brain Electrophysiology in Monkeys.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Traditional methods to access subcortical structures involve the use of anatomical atlases and high precision stereotaxic frames but suffer from significant variations in implantation accuracy. Here, we leveraged the use of the ROSA One(R) Robot Assi...

Working Memory: Delay Activity, Yes! Persistent Activity? Maybe Not.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Persistent spiking has been thought to underlie working memory (WM). However, virtually all of the evidence for this comes from studies that averaged spiking across time and across trials, which masks the details. On single trials, activity often occ...