Objective.Motor imagery brain-computer interfaces hold significant promise for neurorehabilitation, yet their performance is often compromised by electroencephalography (EEG) non-stationarity, low signal-to-noise ratios, and severe cross-session vari...
Journal of neuroengineering and rehabilitation
Oct 29, 2025
BACKGROUND: The therapeutic effect and underlying mechanism of combining transcranial direct current stimulation (tDCS) with robot-assisted gait training (RAGT) for stroke patients remain unclear.
The efficacy of transcranial magnetic stimulation (TMS) is often limited by non-adaptive protocols that disregard instantaneous brain states, potentially constraining therapeutic outcomes. Current EEG-guided approaches are hindered by their reliance ...
Stroke is a leading cause of long-term disability, frequently associated with persistent motor deficits. Gamma band oscillations, generated by synchronous discharge of parvalbumin-positive interneurons (PV-INs), are critically affected after stroke i...
Statistical models are powerful tools for describing biological phenomena such as neuronal spiking activity. Although these models have been widely used to study spontaneous and stimulated neuronal activity, they have not yet been applied to analyze ...
Subthalamic deep brain stimulation (STN-DBS) provides unprecedented spatiotemporal precision for the treatment of Parkinson's disease (PD), allowing for direct real-time state-specific adjustments. Inspired by findings from optogenetic stimulation in...
Closed-loop brain-computer interfaces can be used to bridge, modulate, or repair damaged connections within the brain to restore functional deficits. Towards this goal, we demonstrate that small artificial spiking neural networks can be bidirectional...
Brain-machine interfaces (BMI) aim to restore function to persons living with spinal cord injuries by 'decoding' neural signals into behavior. Recently, nonlinear BMI decoders have outperformed previous state-of-the-art linear decoders, but few studi...
Addiction is a chronic mental disorder caused by disruptions in brain function. While most research has focused on the medial prefrontal cortex, our recent findings highlight the secondary motor cortex (M2) as a key region modulating cocaine-seeking ...
Journal of neuroengineering and rehabilitation
Jun 18, 2025
BACKGROUND: Robot-assisted gait training is more effective in improving lower limb function and walking ability in stroke patients compared to conventional rehabilitation, but the neural mechanisms remain unclear. This study aims to explore the effec...
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