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Heart Failure

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Analysis of Therapeutic Effect of Elderly Patients with Severe Heart Failure Based on LSTM Neural Model.

Computational intelligence and neuroscience
In recent years, cardiovascular-related diseases have become the "number one killer" threatening human life and health and have received much attention. The timely and accurate detection and diagnosis of arrhythmias and heart failure are relatively c...

Deep learning of ECG waveforms for diagnosis of heart failure with a reduced left ventricular ejection fraction.

Scientific reports
The performance and clinical implications of the deep learning aided algorithm using electrocardiogram of heart failure (HF) with reduced ejection fraction (DeepECG-HFrEF) were evaluated in patients with acute HF. The DeepECG-HFrEF algorithm was trai...

AdaDiag: Adversarial Domain Adaptation of Diagnostic Prediction with Clinical Event Sequences.

Journal of biomedical informatics
Early detection of heart failure (HF) can provide patients with the opportunity for more timely intervention and better disease management, as well as efficient use of healthcare resources. Recent machine learning (ML) methods have shown promising pe...

Predicting Mortality in Intensive Care Unit Patients With Heart Failure Using an Interpretable Machine Learning Model: Retrospective Cohort Study.

Journal of medical Internet research
BACKGROUND: Heart failure (HF) is a common disease and a major public health problem. HF mortality prediction is critical for developing individualized prevention and treatment plans. However, due to their lack of interpretability, most HF mortality ...

A method using deep learning to discover new predictors from left-ventricular mechanical dyssynchrony for CRT response.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
BACKGROUND: Studies have shown that the conventional parameters characterizing left ventricular mechanical dyssynchrony (LVMD) measured on gated SPECT myocardial perfusion imaging (MPI) have their own statistical limitations in predicting cardiac res...

Comparison of machine learning and the regression-based EHMRG model for predicting early mortality in acute heart failure.

International journal of cardiology
BACKGROUND: Although risk stratification of patients with acute decompensated heart failure (HF) is important, it is unknown whether machine learning (ML) or conventional statistical models are optimal. We developed ML algorithms to predict 7-day and...

Electronic Health Record-Based Deep Learning Prediction of Death or Severe Decompensation in Heart Failure Patients.

JACC. Heart failure
BACKGROUND: Surgical mechanical ventricular assistance and cardiac replacement therapies, although life-saving in many heart failure (HF) patients, remain high-risk. Despite this, the difficulty in timely identification of medical therapy nonresponde...

Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy.

Science translational medicine
Dilated cardiomyopathy (DCM) is characterized by reduced cardiac output, as well as thinning and enlargement of left ventricular chambers. These characteristics eventually lead to heart failure. Current standards of care do not target the underlying ...

An Explainable Transformer-Based Deep Learning Model for the Prediction of Incident Heart Failure.

IEEE journal of biomedical and health informatics
Predicting the incidence of complex chronic conditions such as heart failure is challenging. Deep learning models applied to rich electronic health records may improve prediction but remain unexplainable hampering their wider use in medical practice....

Dynamic risk stratification using Markov chain modelling in patients with chronic heart failure.

ESC heart failure
AIMS: Risk changes with the progression of disease and the impact of treatment. We developed a dynamic risk stratification Markov chain model using artificial intelligence in patients with chronic heart failure (CHF).