AIMC Topic: Host-Parasite Interactions
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Systems biology of Haemonchus contortus - Advancing biotechnology for parasitic nematode control.
Biotechnology advances
Mar 22, 2025
Parasitic nematodes represent a substantial global burden, impacting animal health, agriculture and economies worldwide. Of these worms, Haemonchus contortus - a blood-feeding nematode of ruminants - is a major pathogen and a model for molecular and ...
Using machine learning to dissect host kinases required for Leishmania internalization and development.
Molecular and biochemical parasitology
Aug 22, 2024
The Leishmania life cycle alternates between promastigotes, found in the sandfly, and amastigotes, found in mammals. When an infected sandfly bites a host, promastigotes are engulfed by phagocytes (i.e., neutrophils, dendritic cells, and macrophages)...
Predicting direct and indirect non-target impacts of biocontrol agents using machine-learning approaches.
PloS one
Jun 1, 2021
Biological pest control (i.e. 'biocontrol') agents can have direct and indirect non-target impacts, and predicting these effects (especially indirect impacts) remains a central challenge in biocontrol risk assessment. The analysis of ecological netwo...
Machine-learning approach expands the repertoire of anti-CRISPR protein families.
Nature communications
Jul 29, 2020
The CRISPR-Cas are adaptive bacterial and archaeal immunity systems that have been harnessed for the development of powerful genome editing and engineering tools. In the incessant host-parasite arms race, viruses evolved multiple anti-defense mechani...
Integrating Microfluidics and Deep Learning to Investigate Entomopathogenic Nematode Responses to Host Cues.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Entomopathogenic nematodes (EPNs) are effective biocontrol agents, reducing pesticide impact on health and the environment. Understanding their physiology and ethology is crucial for optimizing their application. This study offers innovative insights...
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