AIMC Topic: Haemonchus
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Prediction and Prioritisation of Novel Anthelmintic Candidates from Public Databases Using Deep Learning and Available Bioactivity Data Sets.
International journal of molecular sciences
Mar 28, 2025
The control of socioeconomically important parasitic roundworms (nematodes) of animals has become challenging or ineffective due to problems associated with widespread resistance in these worms to most classes of chemotherapeutic drugs (anthelmintics...
Systems biology of Haemonchus contortus - Advancing biotechnology for parasitic nematode control.
Biotechnology advances
Mar 22, 2025
Parasitic nematodes represent a substantial global burden, impacting animal health, agriculture and economies worldwide. Of these worms, Haemonchus contortus - a blood-feeding nematode of ruminants - is a major pathogen and a model for molecular and ...
Inference of Essential Genes of the Parasite via Machine Learning.
International journal of molecular sciences
Jun 27, 2024
Over the years, comprehensive explorations of the model organisms (elegant worm) and (vinegar fly) have contributed substantially to our understanding of complex biological processes and pathways in multicellular organisms generally. Extensive func...
Pharmacokinetic-pharmacodynamic assessment of the ivermectin and abamectin nematodicidal interaction in cattle.
Veterinary parasitology
Dec 10, 2019
In a context of nematodicidal resistance, anthelmintic combinations have emerged as a reliable pharmacological strategy to control gastrointestinal nematodes in grazing systems of livestock production. The current work evaluated the potential drug-dr...
Anthelmintic effect and tissue alterations induced in vitro by hydrolysable tannins on the adult stage of the gastrointestinal nematode Haemonchus contortus.
Veterinary parasitology
Dec 24, 2018
Haemonchus contortus constitutes a severe problem for ruminant's production, it is the most frequent nematode parasite both in template and tropical regions, induces economical losses, and shows increasing resistance to currently available anthelmint...
Anthelmintic Activity of Methanolic Extract from J. Willd Fruits against Eggs and Infective Larvae.
BioMed research international
Nov 29, 2018
The aim of this study was to evaluate the lethal effect of a methanolic extract (ME) from fruits against eggs and infective larvae. The anthelmintic activity was assessed using the egg hatching inhibition assay (EHI) and the mortality test. The ME...
Assessment of anthelmintic activity and bio-guided chemical analysis of Persea americana seed extracts.
Veterinary parasitology
Dec 27, 2017
The aim of this study was to characterize the extracts and fractions of Persea americana Mill. (Avocado) seeds and to determine the composition and the in vitro anthelmintic activity against third-stage larvae (L3) of Haemonchus contortus. The fresh ...
In vitro and in vivo Nematocidal Activity of Allium sativum and Tagetes erecta Extracts Against Haemonchus contortus.
Turkiye parazitolojii dergisi
Dec 1, 2015
OBJECTIVE: In the Mexican ethno-medicine, a number of plants have shown a successful anthelmintic activity. This fact could be crucial to identify possible green anti-parasitic strategies against nematodes affecting animal production. This research e...
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