MOTIVATION: Reactome is a free, open-source, open-data, curated and peer-reviewed knowledgebase of biomolecular pathways. For web-based pathway visualization, Reactome uses a custom pathway diagram viewer that has been evolved over the past years. He...
MOTIVATION: The ever-increasing number of biomedical datasets provides tremendous opportunities for re-use but current data repositories provide limited means of exploration apart from text-based search. Ontological metadata annotations provide conte...
The Reactome Knowledgebase (https://reactome.org) provides molecular details of signal transduction, transport, DNA replication, metabolism, and other cellular processes as an ordered network of molecular transformations-an extended version of a clas...
Protein post-translational modifications (PTMs) play a pivotal role in numerous biological processes by modulating regulation of protein function. We have developed iPTMnet (http://proteininformationresource.org/iPTMnet) for PTM knowledge discovery, ...
Regular monitoring of drug regulatory agency web sites and similar resources for information on new drug approvals and changes to legal status of marketed drugs is impractical. It requires navigation through several resources to find complete informa...
Journal of business continuity & emergency planning
Jan 1, 2018
This paper outlines the importance of organisational resilience and the need for businesses to take a dynamic, innovative and proactive approach in managing risks to their reputation, operations, financial position and viability. It proposes a way of...
In recent years, the amount of video content created and uploaded to the Internet has grown exponentially. Video content has unique accessibility challenges: indexing, transcribing, and searching video has always been very labor intensive, and there ...
Studies in health technology and informatics
Jan 1, 2018
BMI Investigator (BMII) is an interactive web-based tool with a learning knowledge base, which provides a way for researchers to query structured, unstructured, genomic and image data contained in a data warehouse. We demonstrate how development of a...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2018
Toxicity is an important reason for the failure of drug research and development (R&D). The traditional experimental testings for chemical toxicity profile are costly and time-consuming. Therefore, it is attractive to develop the effective and accura...
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