In medicine, the count of different types of white blood cells can be used as the basis for diagnosing certain diseases or evaluating the treatment effects of diseases. The recognition and counting of white blood cells have important clinical signifi...
A blood count is one of the most important diagnostic tools in medicine and one of the most common procedures. It can reveal important changes in the body and is commonly used as the first stage in the process of evaluating patients' health. Even tho...
Whole blood cell analysis is widely used in medical applications since its results are indicators for diagnosing a series of diseases. In this work, we report automatic whole blood cell analysis from blood smear using label-free multi-modal imaging w...
White blood cell (WBC) detection plays a vital role in peripheral blood smear analysis. However, cell detection remains a challenging task due to multi-cell adhesion, different staining and imaging conditions. Owing to the powerful feature extraction...
Label-free image identification of circulating rare cells, such as circulating tumor cells within peripheral blood nucleated cells (PBNCs), the vast majority of which are white blood cells (WBCs), remains challenging. We previously described developi...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
36271498
The five-part differential of leukocytes plays key roles in the diagnosis of a variety of diseases and is realized by optical examinations of single cells, which is prone to various artifacts due to chemical treatments. The classification of leukocyt...
Treatment of blood smears with Wright's stain is one of the most helpful tools in detecting white blood cell abnormalities. However, to diagnose leukocyte disorders, a clinical pathologist must perform a tedious, manual process of locating and identi...
Computer methods and programs in biomedicine
36565666
BACKGROUND AND OBJECTIVES: Visual analysis of cell morphology has an important role in the diagnosis of hematological diseases. Morphological cell recognition is a challenge that requires experience and in-depth review by clinical pathologists. Withi...
The scarcity of training annotation is one of the major challenges for the application of deep learning technology in medical image analysis. Recently, self-supervised learning provides a powerful solution to alleviate this challenge by extracting us...
Clinical chemistry and laboratory medicine
36722042
OBJECTIVES: VEXAS syndrome is a newly described autoinflammatory disease associated with somatic mutations and vacuolization of myeloid precursors. This disease possesses an increasingly broad spectrum, leading to an increase in the number of suspec...