The accurate detection of leukocytes is the basis for the diagnosis of blood system diseases. However, diagnosing leukocyte disorders by doctors is time-consuming and requires extensive experience. Automated detection methods with high accuracy can i...
International journal of laboratory hematology
Feb 3, 2023
INTRODUCTION: A peripheral blood smear is a basic test for hematological disease diagnosis. This test is performed manually in many places worldwide, which requires both time and qualified staff. Large laboratories are equipped with digital morpholog...
Clinical chemistry and laboratory medicine
Feb 2, 2023
OBJECTIVES: VEXAS syndrome is a newly described autoinflammatory disease associated with somatic mutations and vacuolization of myeloid precursors. This disease possesses an increasingly broad spectrum, leading to an increase in the number of suspec...
Computer methods and programs in biomedicine
Dec 15, 2022
BACKGROUND AND OBJECTIVES: Visual analysis of cell morphology has an important role in the diagnosis of hematological diseases. Morphological cell recognition is a challenge that requires experience and in-depth review by clinical pathologists. Withi...
The scarcity of training annotation is one of the major challenges for the application of deep learning technology in medical image analysis. Recently, self-supervised learning provides a powerful solution to alleviate this challenge by extracting us...
Treatment of blood smears with Wright's stain is one of the most helpful tools in detecting white blood cell abnormalities. However, to diagnose leukocyte disorders, a clinical pathologist must perform a tedious, manual process of locating and identi...
In medicine, the count of different types of white blood cells can be used as the basis for diagnosing certain diseases or evaluating the treatment effects of diseases. The recognition and counting of white blood cells have important clinical signifi...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Oct 21, 2022
The five-part differential of leukocytes plays key roles in the diagnosis of a variety of diseases and is realized by optical examinations of single cells, which is prone to various artifacts due to chemical treatments. The classification of leukocyt...
White blood cell (WBC) detection plays a vital role in peripheral blood smear analysis. However, cell detection remains a challenging task due to multi-cell adhesion, different staining and imaging conditions. Owing to the powerful feature extraction...
Whole blood cell analysis is widely used in medical applications since its results are indicators for diagnosing a series of diseases. In this work, we report automatic whole blood cell analysis from blood smear using label-free multi-modal imaging w...
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