Computer methods and programs in biomedicine
Dec 15, 2022
BACKGROUND AND OBJECTIVES: Visual analysis of cell morphology has an important role in the diagnosis of hematological diseases. Morphological cell recognition is a challenge that requires experience and in-depth review by clinical pathologists. Withi...
Journal of biophotonics
Dec 2, 2022
The scarcity of training annotation is one of the major challenges for the application of deep learning technology in medical image analysis. Recently, self-supervised learning provides a powerful solution to alleviate this challenge by extracting us...
Scientific reports
Nov 21, 2022
Treatment of blood smears with Wright's stain is one of the most helpful tools in detecting white blood cell abnormalities. However, to diagnose leukocyte disorders, a clinical pathologist must perform a tedious, manual process of locating and identi...
Journal of healthcare engineering
Nov 9, 2022
In medicine, the count of different types of white blood cells can be used as the basis for diagnosing certain diseases or evaluating the treatment effects of diseases. The recognition and counting of white blood cells have important clinical signifi...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Oct 21, 2022
The five-part differential of leukocytes plays key roles in the diagnosis of a variety of diseases and is realized by optical examinations of single cells, which is prone to various artifacts due to chemical treatments. The classification of leukocyt...
Journal of biophotonics
Sep 29, 2022
White blood cell (WBC) detection plays a vital role in peripheral blood smear analysis. However, cell detection remains a challenging task due to multi-cell adhesion, different staining and imaging conditions. Owing to the powerful feature extraction...
Analytica chimica acta
Sep 15, 2022
Whole blood cell analysis is widely used in medical applications since its results are indicators for diagnosing a series of diseases. In this work, we report automatic whole blood cell analysis from blood smear using label-free multi-modal imaging w...
Lab on a chip
Sep 13, 2022
Label-free image identification of circulating rare cells, such as circulating tumor cells within peripheral blood nucleated cells (PBNCs), the vast majority of which are white blood cells (WBCs), remains challenging. We previously described developi...
IEEE journal of biomedical and health informatics
Aug 11, 2022
White blood cells (WBCs), also known as leukocytes, are one of the valuable parts of the blood and immune system. Typically, pathologists use microscope for the manual inspection of blood smears which is a time-consuming, error-prone, and labor-inten...
BMC bioinformatics
Jul 15, 2022
BACKGROUND: Via counting the different kinds of white blood cells (WBCs), a good quantitative description of a person's health status is obtained, thus forming the critical aspects for the early treatment of several diseases. Thereby, correct classif...