AIMC Topic: Machine Learning

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Artificial intelligence in healthcare: a primer for medical education in radiomics.

Personalized medicine
The application of artificial intelligence (AI) to healthcare has garnered significant enthusiasm in recent years. Despite the adoption of new analytic approaches, medical education on AI is lacking. We aim to create a usable AI primer for medical ed...

Optimisation of Deep Learning Small-Object Detectors with Novel Explainable Verification.

Sensors (Basel, Switzerland)
In this paper, we present a novel methodology based on machine learning for identifying the most appropriate from a set of available state-of-the-art object detectors for a given application. Our particular interest is to develop a road map for ident...

Survival prediction models: an introduction to discrete-time modeling.

BMC medical research methodology
BACKGROUND: Prediction models for time-to-event outcomes are commonly used in biomedical research to obtain subject-specific probabilities that aid in making important clinical care decisions. There are several regression and machine learning methods...

A novel biomarker selection method combining graph neural network and gene relationships applied to microarray data.

BMC bioinformatics
BACKGROUND: The discovery of critical biomarkers is significant for clinical diagnosis, drug research and development. Researchers usually obtain biomarkers from microarray data, which comes from the dimensional curse. Feature selection in machine le...

Machine learning in the loop for tuberculosis diagnosis support.

Frontiers in public health
The use of machine learning (ML) for diagnosis support has advanced in the field of health. In the present paper, the results of studying ML techniques in a tuberculosis diagnosis loop in a scenario of limited resources are presented. Data are analyz...

SCORCH: Improving structure-based virtual screening with machine learning classifiers, data augmentation, and uncertainty estimation.

Journal of advanced research
INTRODUCTION: The discovery of a new drug is a costly and lengthy endeavour. The computational prediction of which small molecules can bind to a protein target can accelerate this process if the predictions are fast and accurate enough. Recent machin...

A process mining- deep learning approach to predict survival in a cohort of hospitalized COVID-19 patients.

BMC medical informatics and decision making
BACKGROUND: Various machine learning and artificial intelligence methods have been used to predict outcomes of hospitalized COVID-19 patients. However, process mining has not yet been used for COVID-19 prediction. We developed a process mining/deep l...

Matrix factorization with denoising autoencoders for prediction of drug-target interactions.

Molecular diversity
Drug-target interaction is crucial in the discovery of new drugs. Computational methods can be used to identify new drug-target interactions at low costs and with reasonable accuracy. Recent studies pay more attention to machine-learning methods, ran...

In-depth evaluation of machine learning methods for semi-automating article screening in a systematic review of mechanistic literature.

Research synthesis methods
We aimed to evaluate the performance of supervised machine learning algorithms in predicting articles relevant for full-text review in a systematic review. Overall, 16,430 manually screened titles/abstracts, including 861 references identified releva...

Prediction of protein mononucleotide binding sites using AlphaFold2 and machine learning.

Computational biology and chemistry
In this study, we developed a system that predicts the binding sites of proteins for five mononucleotides (AMP, ADP, ATP, GDP, and GTP). The system comprises two machine learning (ML)-based predictors using a convolutional neural network and a gradie...