Methods in molecular biology (Clifton, N.J.)
Jan 1, 2022
Cell images provide a multitude of phenotypic information, which in its entirety the human eye can hardly perceive. Automated image analysis and machine learning approaches enable the unbiased identification and analysis of cellular mechanisms and as...
IEEE transactions on image processing : a publication of the IEEE Signal Processing Society
Jan 1, 2022
Advanced shape analysis studies such as regression and classification need to be performed on curved manifolds, where often, there is a lack of standard statistical formulations. To overcome these limitations, we introduce a novel machine-learning me...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2022
Antibiotic resistance constitutes a global threat and could lead to a future pandemic. One strategy is to develop a new generation of antimicrobials. Naturally occurring antimicrobial peptides (AMPs) are recognized templates and some are already in c...
Binding free energy estimation of drug candidates to their biomolecular target is one of the best quantitative estimators in computer-aided drug discovery. Accurate binding free energy estimation is still a challengeable task even after decades of re...
Although the therapeutic efficacy and commercial success of monoclonal antibodies (mAbs) are tremendous, the design and discovery of new candidates remain a time and cost-intensive endeavor. In this regard, progress in the generation of data describi...
Journal of X-ray science and technology
Jan 1, 2022
BACKGROUND: Processing Low-Intensity Medical Images (LI-MI) is difficult as outcomes are varied when it comes to manual examination, which is also a time-consuming process.
The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics
Jan 1, 2022
When applied in the health sector, AI-based applications raise not only ethical but legal and safety concerns, where algorithms trained on data from majority populations can generate less accurate or reliable results for minorities and other disadvan...
Advances in experimental medicine and biology
Jan 1, 2022
Precision oncology is an innovative approach to cancer care in which diagnosis, prognosis, and treatment are informed by the individual patient's genetic and molecular profile. The rapid development of novel high-throughput omics technologies in rece...
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