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Microscopy

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Evaluation of an Artificial Intelligence-Based Tool and a Universal Low-Cost Robotized Microscope for the Automated Diagnosis of Malaria.

International journal of environmental research and public health
The gold standard diagnosis for malaria is the microscopic visualization of blood smears to identify parasites, although it is an expert-dependent technique and could trigger diagnostic errors. Artificial intelligence (AI) tools based on digital ima...

Deep learning enabled rapid classification of yeast species in food by imaging of yeast microcolonies.

Food research international (Ottawa, Ont.)
Diverse species of yeasts are commonly associated with food and food production environments. The contamination of food products by spoilage yeasts poses significant challenges, leading to quality degradation and food loss. Similarly, the introductio...

VGX: VGG19-Based Gradient Explainer Interpretable Architecture for Brain Tumor Detection in Microscopy Magnetic Resonance Imaging (MMRI).

Microscopy research and technique
The development of deep learning algorithms has transformed medical image analysis, especially in brain tumor recognition. This research introduces a robust automatic microbrain tumor identification method utilizing the VGG16 deep learning model. Mic...

Data stewardship and curation practices in AI-based genomics and automated microscopy image analysis for high-throughput screening studies: promoting robust and ethical AI applications.

Human genomics
BACKGROUND: Researchers have increasingly adopted AI and next-generation sequencing (NGS), revolutionizing genomics and high-throughput screening (HTS), and transforming our understanding of cellular processes and disease mechanisms. However, these a...

Using Machine Learning and Optical Microscopy Image Analysis of Immunosensors Made on Plasmonic Substrates: Application to Detect the SARS-CoV-2 Virus.

ACS sensors
In this article, we introduce a diagnostic platform comprising an optical microscopy image analysis system coupled with machine learning. Its efficacy is demonstrated in detecting SARS-CoV-2 virus particles at concentrations as low as 1 PFU (plaque-f...

Machine learning with label-free Raman microscopy to investigate ferroptosis in comparison with apoptosis and necroptosis.

Communications biology
Human and animal health rely on balancing cell division and cell death to maintain normal homeostasis. This process is accomplished by regulated cell death (RCD), whose imbalance can lead to disease. Currently, the most frequently used method for ana...

Machine learning models for segmentation and classification of cyanobacterial cells.

Photosynthesis research
Timelapse microscopy has recently been employed to study the metabolism and physiology of cyanobacteria at the single-cell level. However, the identification of individual cells in brightfield images remains a significant challenge. Traditional inten...

Accelerating biopharmaceutical cell line selection with label-free multimodal nonlinear optical microscopy and machine learning.

Communications biology
The selection of high-performing cell lines is crucial for biopharmaceutical production but is often time-consuming and labor-intensive. We investigated label-free multimodal nonlinear optical microscopy for non-perturbative profiling of biopharmaceu...

Detecting living microalgae in ship ballast water based on stained microscopic images and deep learning.

Marine pollution bulletin
Motivated by the need of rapid detection of living microalgae cells in ship ballast water, this study is intended to determine the activities of microalgae using stained microscopic images and detect the living cells with image processing algorithms....

Tissue Clutter Filtering Methods in Ultrasound Localization Microscopy Based on Complex-Valued Networks and Knowledge Distillation.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control
Ultrasound localization microscopy (ULM) is a blood flow imaging technique that utilizes micrometer-sized microbubbles (MBs) as contrast agents to achieve high-resolution microvessel reconstruction through precise localization and tracking of MBs. Th...