Cancer of bone marrow is classified as Acute Lymphoblastic Leukemia (ALL), an abnormal growth of lymphoid progenitor cells. It affects both children and adults and is the most predominant form of infantile cancer. Currently, there has been significan...
Long-term and high-spatiotemporal-resolution 3D imaging of living cells remains an unmet challenge for super-resolution microscopy, owing to the noticeable phototoxicity and limited scanning speed. While emerging light-field microscopy can mitigate t...
Leukemia is a hematologic tumor that proliferates in bone marrow and seriously affects the survival of patients. Early and accurate diagnosis is crucial for effective leukemia treatment. Traditional diagnostic methods rely on experts' subjective anal...
BACKGROUND: Organoids have attracted enormous interest in disease modeling, drug screening, and precision medicine. However, developing robust patient-derived organoids (PDOs) was time-consuming, costly, and had low success rates for certain cancer t...
The process of protein aggregation, central to neurodegenerative diseases like Huntington's, is challenging to study due to its unpredictable nature and relatively rapid kinetics. Understanding its biomechanics is crucial for unraveling its role in d...
Myocardial infarction, a leading cause of mortality worldwide, leaves survivors at significant risk of recurrence caused by scar-related re-entrant ventricular tachyarrhythmias. Effective treatment with ablation therapy requires a precise guidance sy...
Microscopic-Diffraction Imaging Flow Cytometry (MDIFC) is a high-throughput, stain-free technology that captures paired microscopic and diffraction images of cellular events, utilizing machine learning for the classification of cell subpopulations. H...
Super-resolution imaging has emerged as a rapidly advancing field in diagnostic ultrasound. Ultrasound Localization Microscopy (ULM) achieves sub-wavelength precision in microvasculature imaging by tracking gas microbubbles (MBs) flowing through bloo...
Label-free optical imaging of the morphology of single nanoparticles under native conditions remains a challenging task despite its importance in the synthesis, properties, and applications of nanomaterials. Here, we developed an angular scanning dar...
In this work, we developed an automated system for the detection and classification of soil-transmitted helminths (STH) and Schistosoma (S.) mansoni eggs in microscopic images of fecal smears. We assembled an STH and S. mansoni dataset comprising ove...
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