AI Medical Compendium Topic

Explore the latest research on artificial intelligence and machine learning in medicine.

Mitogen-Activated Protein Kinase 14

Showing 1 to 3 of 3 articles

Clear Filters

Visualization and Interpretation of Support Vector Machine Activity Predictions.

Journal of chemical information and modeling 25988274
Support vector machines (SVMs) are among the preferred machine learning algorithms for virtual compound screening and activity prediction because of their frequently observed high performance levels. However, a well-known conundrum of SVMs (and other...
Algorithms Drug Evaluation, Preclinical Humans Ligands Linear Models Mitogen-Activated Protein Kinase 14 Protein Kinase Inhibitors Receptor, Cannabinoid, CB2 Receptors, Dopamine D2 Software Support Vector Machine
View on PubMed DOI

TIGERi: modeling and visualizing the responses to perturbation of a transcription factor network.

BMC bioinformatics 28617232
BACKGROUND: Transcription factor (TF) networks play a key role in controlling the transfer of genetic information from gene to mRNA. Much progress has been made on understanding and reverse-engineering TF network topologies using a range of experimen...
Animals Binding Sites Gene Regulatory Networks Machine Learning Mice Mice, Knockout Mitogen-Activated Protein Kinase 14 Transcription Factors Transcriptome
View on PubMed DOI

Binding mechanism of inhibitors to DFG-in and DFG-out P38α deciphered using multiple independent Gaussian accelerated molecular dynamics simulations and deep learning.

SAR and QSAR in environmental research 40110797
P38α has been identified as a key target for drug design to treat a wide range of diseases. In this study, multiple independent Gaussian accelerated molecular dynamics (GaMD) simulations, deep learning (DL), and the molecular mechanics generalized Bo...
Deep Learning Drug Design Mitogen-Activated Protein Kinase 14 Molecular Dynamics Simulation Protein Binding Quantitative Structure-Activity Relationship
View on PubMed DOI
Popular Topics
Recent Journals