AIMC Topic: Models, Biological

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Learning control-ready forecasters for Blood Glucose Management.

Computers in biology and medicine
Type 1 diabetes (T1D) presents a significant health challenge, requiring patients to actively manage their blood glucose (BG) levels through regular bolus insulin administration. Automated control solutions based on machine learning (ML) models could...

Universal optimal design in the vertebrate limb pattern and lessons for bioinspired design.

Bioinspiration & biomimetics
This paper broadly summarizes the variation of design features found in vertebrate limbs and analyses the resultant versatility and multifunctionality in order to make recommendations for bioinspired robotics. The vertebrate limb pattern (e.g. should...

Visually guided swarm motion coordination via insect-inspired small target motion reactions.

Bioinspiration & biomimetics
Despite progress developing experimentally-consistent models of insect in-flight sensing and feedback for individual agents, a lack of systematic understanding of the multi-agent and group performance of the resulting bio-inspired sensing and feedbac...

Design of a bipedal robot for water running based on a six-linkage mechanism inspired by basilisk lizards.

Bioinspiration & biomimetics
Legged robots have received widespread attention in academia and engineering owing to their excellent terrain adaptability. However, most legged robots can only adapt to high-hardness environments instead of flexible environments. Expanding the motio...

Predicting Knee Joint Contact Force Peaks During Gait Using a Video Camera or Wearable Sensors.

Annals of biomedical engineering
PURPOSE: Estimating loading of the knee joint may be helpful in managing degenerative joint diseases. Contemporary methods to estimate loading involve calculating knee joint contact forces using musculoskeletal modeling and simulation from motion cap...

Synthetic 3D full-body skeletal motion from 2D paths using RNN with LSTM cells and linear networks.

Computers in biology and medicine
Gait analysis has proven to be a key process in the functional assessment of people involving many fields, such as diagnosis of diseases or rehabilitation, and has increased in relevance lately. Gait analysis often requires gathering data, although t...

A Machine Learning Algorithm to Predict the Starting Dose of Daptomycin.

Clinical pharmacokinetics
BACKGROUND AND OBJECTIVE: The dosage of daptomycin is usually based on body weight. However, it has been shown that this approach yields too high an exposure in obese patients. Pharmacokinetic and pharmacodynamic indexes (PK/PD) have been proposed fo...

Using deep learning for predicting the dynamic evolution of breast cancer migration.

Computers in biology and medicine
BACKGROUND: Breast cancer (BC) remains a prevalent health concern, with metastasis as the main driver of mortality. A detailed understanding of metastatic processes, particularly cell migration, is fundamental to improve therapeutic strategies. The w...

Quantifying massively parallel microbial growth with spatially mediated interactions.

PLoS computational biology
Quantitative understanding of microbial growth is an essential prerequisite for successful control of pathogens as well as various biotechnology applications. Even though the growth of cell populations has been extensively studied, microbial growth r...

Cell factory design with advanced metabolic modelling empowered by artificial intelligence.

Metabolic engineering
Advances in synthetic biology and artificial intelligence (AI) have provided new opportunities for modern biotechnology. High-performance cell factories, the backbone of industrial biotechnology, are ultimately responsible for determining whether a b...