Cells are the basic units of biological organization, and the quantitative analysis of cellular states is an important topic in medicine and is valuable in revealing the complex mechanisms of microscopic world organisms. In order to better understand...
A variety of new recurrent neural networks (RNNs) including the ODE-LSTM, Phased LSTM, CTGRU and GRU-D, were evaluated on modeling irregularly sampled PK/PD data with 6 or 12 time points/day and predicting PD data of unseen dosing regimens and dosing...
Flight control such as stable hovering and trajectory tracking of tailless flapping-wing micro aerial vehicles is a challenging task. Given the constraint on actuation capability, flight control authority is limited beyond sufficient lift generation....
Journal of chemical information and modeling
Jan 3, 2023
Although computational predictions of pharmacokinetics (PK) are desirable at the drug design stage, existing approaches are often limited by prediction accuracy and human interpretability. Using a discovery data set of mouse and rat PK studies at Roc...
In order to improve the tracking adaptability of autonomous vehicles under different vehicle speeds and road curvature, this paper develops a weight adaptive model prediction control system (AMPC) based on PSO-BP neural network, which consists of a d...
Traditional flapping-wing robots (FWRs) obtain lift and thrust by relying on the passive deformation of their wings which cannot actively fold or deform. In contrast, flying creatures such as birds, bats, and insects can maneuver agilely through acti...
In recent years, Vehicle Make and Model Recognition (VMMR) has attracted a lot of attention as it plays a crucial role in Intelligent Transportation Systems (ITS). Accurate and efficient VMMR systems are required in real-world applications including ...
Attitude control is an essential flight capability. Whereas flying robots commonly rely on accelerometers for estimating attitude, flying insects lack an unambiguous sense of gravity. Despite the established role of several sense organs in attitude s...
CPT: pharmacometrics & systems pharmacology
Oct 12, 2022
The gold-standard approach for modeling pharmacokinetic mediated drug-drug interactions is the use of physiologically-based pharmacokinetic modeling and population pharmacokinetics. However, these models require extensive amounts of drug-specific dat...
The knee joint plays a key role in kinematic and kinetic performances of pedestrain locomotion. The key role of meniscus with matched ligaments in joint stability and movability has not been fully explored in current robotic knee designs. We fabricat...