AIMC Topic: Molecular Sequence Data

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Crystallization and X-ray diffraction of an ectoine hydroxylase from Bacillus pseudofirmus OF4.

Wei sheng wu xue bao = Acta microbiologica Sinica Nov 4, 2015
OBJECTIVE: To study crystallization and X-Ray diffraction of ectoine hydroxylase from Bacillus pseudofirmus OF4.
Amino Acids, Diamino Mixed Function Oxygenases Sequence Alignment Bacterial Proteins Crystallization Amino Acid Sequence Bacillus X-Ray Diffraction Molecular Sequence Data
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[Alkaline-adapted beta-mannanase of Bacillus pumilus: gene heterologous expression and enzyme characterization].

Wei sheng wu xue bao = Acta microbiologica Sinica Nov 4, 2015
OBJECTIVE: We expressed a novel alkaline-adapted beta-mannanase gene and characterized the enzyme for potential industrial applications.
Phylogeny Escherichia coli Gene Expression beta-Mannosidase Bacterial Proteins Sequence Alignment Enzyme Stability Kinetics Alkalies Amino Acid Sequence Base Sequence Cloning, Molecular Bacillus Molecular Sequence Data
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AVP-IC50 Pred: Multiple machine learning techniques-based prediction of peptide antiviral activity in terms of half maximal inhibitory concentration (IC50).

Biopolymers Nov 1, 2015
Peptide-based antiviral therapeutics has gradually paved their way into mainstream drug discovery research. Experimental determination of peptides' antiviral activity as expressed by their IC50 values involves a lot of effort. Therefore, we have deve...
Machine Learning Internet Amino Acid Sequence Inhibitory Concentration 50 Molecular Sequence Data Algorithms Peptides Antiviral Agents
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[Screening and identification of antioxidant endophytes from Lycium barbarum of Ningxia].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica Oct 1, 2015
In this paper, 29 endophytes were isolated from different organs and tissues of Lycium barbarum of Ningxia by tablet coating method, 18 of them was fungi, and 11 of them was actinomycetes. The endophytes quantity in the different tissues were leaves ...
Lycium Bacteria Antioxidants Oxidation-Reduction Fungi Biodiversity Molecular Sequence Data Endophytes
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Predicting Protein-Protein Interaction Sites with a Novel Membership Based Fuzzy SVM Classifier.

IEEE/ACM transactions on computational biology and bioinformatics Jan 1, 2015
Predicting residues that participate in protein-protein interactions (PPI) helps to identify, which amino acids are located at the interface. In this paper, we show that the performance of the classical support vector machine (SVM) algorithm can furt...
Algorithms Computer Simulation Protein Binding Fuzzy Logic Humans Sequence Alignment Sequence Analysis, Protein Pattern Recognition, Automated Binding Sites Protein Interaction Mapping Molecular Sequence Data Models, Statistical Models, Chemical Amino Acid Sequence
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A Machine Learning Based Approach to de novo Sequencing of Glycans from Tandem Mass Spectrometry Spectrum.

IEEE/ACM transactions on computational biology and bioinformatics Jan 1, 2015
Recently, glycomics has been actively studied and various technologies for glycomics have been rapidly developed. Currently, tandem mass spectrometry (MS/MS) is one of the key experimental tools for identification of structures of oligosaccharides. M...
Molecular Sequence Data Sequence Analysis Glycomics Tandem Mass Spectrometry Pattern Recognition, Automated Carbohydrate Sequence Machine Learning Algorithms Reproducibility of Results Sensitivity and Specificity Polysaccharides
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Genome-wide discovery of miRNAs using ensembles of machine learning algorithms and logistic regression.

International journal of data mining and bioinformatics Jan 1, 2015
In silico prediction of novel miRNAs from genomic sequences remains a challenging problem. This study presents a genome-wide miRNA discovery software package called GenoScan and evaluates two hairpin classification methods. These methods, one ensembl...
Sequence Analysis, RNA MicroRNAs Regression Analysis Pattern Recognition, Automated Base Sequence Genome, Human Inverted Repeat Sequences Humans Machine Learning Algorithms Logistic Models Molecular Sequence Data Chromosome Mapping
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Sequence based human leukocyte antigen gene prediction using informative physicochemical properties.

International journal of data mining and bioinformatics Jan 1, 2015
Prediction of different classes within the human leukocyte antigen (HLA) gene family can provide insight into the human immune system and its response to viral pathogens. Therefore, it is desirable to develop an efficient and easily interpretable met...
Leukocytes Algorithms Pattern Recognition, Automated Amino Acid Sequence Humans Data Mining Support Vector Machine Molecular Sequence Data Databases, Protein Sequence Analysis, Protein Structure-Activity Relationship HLA-A Antigens
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Exploiting multi-layered vector spaces for signal peptide detection.

International journal of data mining and bioinformatics Jan 1, 2015
Analysing and classifying sequences based on similarities and differences is a mathematical problem of escalating relevance and importance in many scientific disciplines. One of the primary challenges in applying machine learning algorithms to sequen...
Molecular Sequence Data Sequence Alignment Sequence Analysis, Protein Protein Sorting Signals Databases, Protein Algorithms Amino Acid Sequence Peptides Data Mining Support Vector Machine Pattern Recognition, Automated
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A novel fractal approach for predicting G-protein-coupled receptors and their subfamilies with support vector machines.

Bio-medical materials and engineering Jan 1, 2015
G-protein-coupled receptors (GPCRs) are seven membrane-spanning proteins and regulate many important physiological processes, such as vision, neurotransmission, immune response and so on. GPCRs-related pathways are the targets of a large number of ma...
Data Mining Pattern Recognition, Automated Molecular Sequence Data Sequence Alignment Receptors, G-Protein-Coupled Structure-Activity Relationship Amino Acid Sequence Sequence Analysis, Protein Fractals Algorithms Support Vector Machine Databases, Protein
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