MOTIVATION: A single gene may yield several isoforms with different functions through alternative splicing. Continuous efforts are devoted to developing machine-learning methods to predict isoform functions. However, existing methods do not consider ...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2023
Monte Carlo eXtreme (MCX) method has a unique advantage for deep neural network based bioluminescence tomography (BLT) reconstruction. However, this method ignores the distribution of sources energy and relies on the determined tissue structure. In t...
Computational hemodynamic modeling has been widely used in cardiovascular research and healthcare. However, the reliability of model predictions is largely dependent on the uncertainties of modeling parameters and boundary conditions, which should be...
Accurate ab initio calculations are of fundamental importance in physics, chemistry, biology, and materials science, which have witnessed rapid development in the last couple of years with the help of machine learning computational techniques such as...
Equilibrium structures determine material properties and biochemical functions. We here propose to machine learn phase space averages, conventionally obtained by ab initio or force-field-based molecular dynamics (MD) or Monte Carlo (MC) simulations. ...
We present a parallel Monte Carlo (MC) simulation platform for rapidly generating synthetic common-path optical coherence tomography (CP-OCT) A-scan image dataset for image-guided needle insertion. The computation time of the method has been evaluate...
MOTIVATION: Interactions between peptide fragments and protein receptors are vital to cell function yet difficult to experimentally determine in structural details of. As such, many computational methods have been developed to aid in peptide-protein ...
SIGNIFICANCE: The Monte Carlo (MC) method is widely used as the gold-standard for modeling light propagation inside turbid media, such as human tissues, but combating its inherent stochastic noise requires one to simulate a large number photons, resu...
SIGNIFICANCE: To achieve early detection of osteoporosis, a simple bone densitometry method using optics was proposed. However, individual differences in soft tissue structure and optical properties can cause errors in quantitative bone densitometry....
SIGNIFICANCE: Deep learning (DL) models are being increasingly developed to map sensor data to the image domain directly. However, DL methodologies are data-driven and require large and diverse data sets to provide robust and accurate image formation...
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