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Nanomedicine

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Bioinspired microrobots: Opportunities and challenges in targeted cancer therapy.

Journal of controlled release : official journal of the Controlled Release Society
Chemotherapy is still the most effective technique to treat many forms of cancer. However, it also carries a high risk of side effects. Numerous nanomedicines have been developed to avoid unintended consequences and significant negative effects of co...

Medical microrobots in reproductive medicine from the bench to the clinic.

Nature communications
Medical microrobotics is an emerging field that aims at non-invasive diagnosis and therapy inside the human body through miniaturized sensors and actuators. Such microrobots can be tethered (e.g., smart microcatheters, microendoscopes) or untethered ...

Artificial intelligence and machine learning disciplines with the potential to improve the nanotoxicology and nanomedicine fields: a comprehensive review.

Archives of toxicology
The use of nanomaterials in medicine depends largely on nanotoxicological evaluation in order to ensure safe application on living organisms. Artificial intelligence (AI) and machine learning (MI) can be used to analyze and interpret large amounts of...

Chemical tunability of advanced materials used in the fabrication of micro/nanobots.

Journal of materials chemistry. B
Micro and nanobots (MNBs) are unprecedented in their ability to be chemically tuned for autonomous tasks with enhanced targeting and functionality while maintaining their mobility. A myriad of chemical modifications involving a large variety of advan...

Knowledge Gaps in Generating Cell-Based Drug Delivery Systems and a Possible Meeting with Artificial Intelligence.

Molecular pharmaceutics
Cell-based drug delivery systems are new strategies in targeted delivery in which cells or cell-membrane-derived systems are used as carriers and release their cargo in a controlled manner. Recently, great attention has been directed to cells as carr...

Feeding Next-Generation Nanomedicines to Europe: Regulatory and Quality Challenges.

Advanced healthcare materials
New and innovative nanomedicines have been developed and marketed over the past half-century, revolutionizing the prognosis of many human diseases. Although a univocal regulatory definition is not yet available worldwide, the term "nanomedicines" gen...

Deep learning for automatic organ and tumor segmentation in nanomedicine pharmacokinetics.

Theranostics
: Multimodal imaging provides important pharmacokinetic and dosimetry information during nanomedicine development and optimization. However, accurate quantitation is time-consuming, resource intensive, and requires anatomical expertise. : We present ...

Decoding Nanomaterial-Biosystem Interactions through Machine Learning.

Angewandte Chemie (International ed. in English)
The interactions between biosystems and nanomaterials regulate most of their theranostic and nanomedicine applications. These nanomaterial-biosystem interactions are highly complex and influenced by a number of entangled factors, including but not li...

A large-scale machine learning analysis of inorganic nanoparticles in preclinical cancer research.

Nature nanotechnology
Owing to their distinct physical and chemical properties, inorganic nanoparticles (NPs) have shown promising results in preclinical cancer therapy, but designing and engineering them for effective therapeutic purposes remains a challenge. Although a ...