AIMC Topic: Neoplasms

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Deep Survival Analysis With Latent Clustering and Contrastive Learning.

IEEE journal of biomedical and health informatics
Survival analysis is employed to analyze the time before the event of interest occurs, which is broadly applied in many fields. The existence of censored data with incomplete supervision information about survival outcomes is one key challenge in sur...

Agent-based approaches for biological modeling in oncology: A literature review.

Artificial intelligence in medicine
CONTEXT: Computational modeling involves the use of computer simulations and models to study and understand real-world phenomena. Its application is particularly relevant in the study of potential interactions between biological elements. It is a pro...

Harnessing TME depicted by histological images to improve cancer prognosis through a deep learning system.

Cell reports. Medicine
Spatial transcriptomics (ST) provides insights into the tumor microenvironment (TME), which is closely associated with cancer prognosis, but ST has limited clinical availability. In this study, we provide a powerful deep learning system to augment TM...

UNNT: A novel Utility for comparing Neural Net and Tree-based models.

PLoS computational biology
The use of deep learning (DL) is steadily gaining traction in scientific challenges such as cancer research. Advances in enhanced data generation, machine learning algorithms, and compute infrastructure have led to an acceleration in the use of deep ...

Application of machine learning for high-throughput tumor marker screening.

Life sciences
High-throughput sequencing and multiomics technologies have allowed increasing numbers of biomarkers to be mined and used for disease diagnosis, risk stratification, efficacy assessment, and prognosis prediction. However, the large number and complex...

Improving chimeric antigen receptor T-cell therapies by using artificial intelligence and internet of things technologies: A narrative review.

European journal of pharmacology
Cancer poses a formidable challenge in the field of medical science, prompting the exploration of innovative and efficient treatment strategies. One revolutionary breakthrough in cancer therapy is Chimeric Antigen Receptor (CAR) T-cell therapy, an av...

Essentiality, protein-protein interactions and evolutionary properties are key predictors for identifying cancer-associated genes using machine learning.

Scientific reports
The distinctive nature of cancer as a disease prompts an exploration of the special characteristics the genes implicated in cancer exhibit. The identification of cancer-associated genes and their characteristics is crucial to further our understandin...

Tissue specific tumor-gene link prediction through sampling based GNN using a heterogeneous network.

Medical & biological engineering & computing
A tissue sample is a valuable resource for understanding a patient's symptoms and health status in relation to tumor growth. Recent research seeks to establish a connection between tissue-specific tumor samples and genetic markers (genes). This break...