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Neural Inhibition

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Long-range recruitment of Martinotti cells causes surround suppression and promotes saliency in an attractor network model.

Frontiers in neural circuits
Although the importance of long-range connections for cortical information processing has been acknowledged for a long time, most studies focused on the long-range interactions between excitatory cortical neurons. Inhibitory interneurons play an impo...

Regulation of Local Ambient GABA Levels via Transporter-Mediated GABA Import and Export for Subliminal Learning.

Neural computation
Perception of supraliminal stimuli might in general be reflected in bursts of action potentials (spikes), and their memory traces could be formed through spike-timing-dependent plasticity (STDP). Memory traces for subliminal stimuli might be formed i...

Periodic solution for state-dependent impulsive shunting inhibitory CNNs with time-varying delays.

Neural networks : the official journal of the International Neural Network Society
In this paper, we consider existence and global exponential stability of periodic solution for state-dependent impulsive shunting inhibitory cellular neural networks with time-varying delays. By means of B-equivalence method, we reduce these state-de...

Impaired dendritic inhibition leads to epileptic activity in a computer model of CA3.

Hippocampus
Temporal lobe epilepsy (TLE) is a common type of epilepsy with hippocampus as the usual site of origin. The CA3 subfield of hippocampus is reported to have a low epileptic threshold and hence initiates the disorder in patients with TLE. This study co...

Inhibition facilitates direction selectivity in a noisy cortical environment.

Journal of computational neuroscience
In a broad class of models, direction selectivity in primary visual cortical neurons arises from the linear summation of spatially offset and temporally lagged inputs combined with a spike threshold. Here, we characterize the robustness of this class...

Speed-accuracy tradeoff by a control signal with balanced excitation and inhibition.

Journal of neurophysiology
A hallmark of flexible behavior is the brain's ability to dynamically adjust speed and accuracy in decision-making. Recent studies suggested that such adjustments modulate not only the decision threshold, but also the rate of evidence accumulation. H...

GABA diffusion across neuronal columns for efficient sensory tuning.

Biological cybernetics
Synaptic (phasic) lateral inhibition between neuronal columns mediated by GABAergic interneurons is, in general, essential for primary sensory cortices to respond selectively to elemental features. We propose here a neural network model with a nonsyn...

Short-term effect of electrical nerve stimulation on spinal reciprocal inhibition during robot-assisted passive stepping in humans.

The European journal of neuroscience
The purpose of this study was to investigate the effect of electrical stimulation to the common peroneal nerve (CPN) on the spinal reflex and reciprocal inhibition (RI) during robot-assisted passive ground stepping (PGS) in healthy subjects. Five int...