A drop in physical activity and a deterioration in the capacity to undertake daily life activities are both connected with ageing and have negative effects on physical and mental health. An Elderly and Visually Impaired Human Activity Monitoring (EV-...
There is increasing interest in the application of Raman spectroscopy in a medical setting, ranging from supporting real-time clinical decisions surgical margins to assisting pathologists with disease classification. However, there remain a number o...
BACKGROUND/AIMS: Image quality assessment (IQA) is crucial for both reading centres in clinical studies and routine practice, as only adequate quality allows clinicians to correctly identify diseases and treat patients accordingly. Here we aim to dev...
Neural networks : the official journal of the International Neural Network Society
Dec 17, 2023
Modern DNNs often include a huge number of parameters that are expensive for both computation and memory. Pruning can significantly reduce model complexity and lessen resource demands, and less complex models can also be easier to explain and interpr...
Monitoring heart electrical activity is an effective way of detecting existing and developing conditions. This is usually performed as a non-invasive test using a network of up to 12 sensors (electrodes) on the chest and limbs to create an electrocar...
BACKGROUND: In the field of computational personalized medicine, drug response prediction (DRP) is a critical issue. However, existing studies often characterize drugs as strings, a representation that does not align with the natural description of m...
Interdisciplinary sciences, computational life sciences
Dec 16, 2023
Drug repositioning is critical to drug development. Previous drug repositioning methods mainly constructed drug-disease heterogeneous networks to extract drug-disease features. However, these methods faced difficulty when we are using structurally si...
Journal of chemical information and modeling
Dec 16, 2023
Drug repositioning plays a key role in disease treatment. With the large-scale chemical data increasing, many computational methods are utilized for drug-disease association prediction. However, most of the existing models neglect the positive influe...
The clinical applications of brain age prediction have expanded, particularly in anticipating the onset and prognosis of various neurodegenerative diseases. In the current study, we proposed a deep learning algorithm that leverages brain structural i...
Journal of biomolecular structure & dynamics
Dec 15, 2023
The enzyme dipeptidyl peptidase 4 (DPP4) is a potential therapeutic target for type 2 diabetes (T2DM). Many synthetic anti-DPP4 medications are available to treat T2DM. The need for secure and efficient medicines has been unmet due to the adverse sid...
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