AIMC Topic: Organ Specificity
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Machine learning in computational biology to accelerate high-throughput protein expression.
Bioinformatics (Oxford, England)
Aug 15, 2017
MOTIVATION: The Human Protein Atlas (HPA) enables the simultaneous characterization of thousands of proteins across various tissues to pinpoint their spatial location in the human body. This has been achieved through transcriptomics and high-throughp...
Identification of human flap endonuclease 1 (FEN1) inhibitors using a machine learning based consensus virtual screening.
Molecular bioSystems
Jul 25, 2017
Human Flap endonuclease1 (FEN1) is an enzyme that is indispensable for DNA replication and repair processes and inhibition of its Flap cleavage activity results in increased cellular sensitivity to DNA damaging agents (cisplatin, temozolomide, MMS, e...
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