AIMC Topic: Sulfites
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An appropriate DNA input for bisulfite conversion reveals LINE-1 and Alu hypermethylation in tissues and circulating cell-free DNA from cancers.
PloS one
Dec 30, 2024
The autonomous and active Long-Interspersed Element-1 (LINE-1, L1) and the non-autonomous Alu retrotransposon elements, contributing to 30% of the human genome, are the most abundant repeated sequences. With more than 90% of their sequences being met...
Unveiling the role of artificial intelligence in tetracycline antibiotics removal using UV/sulfite/phenol advanced reduction process.
Journal of environmental management
Sep 14, 2024
UV/sulfite-based advanced reduction processes (ARP) have attracted increasing attention due to their high capability for removing a wide range of pollutants. Therefore, developing UV/sulfite ARP systems with assisted Artificial Intelligence (AI) mode...
ME-Class2 reveals context dependent regulatory roles for 5-hydroxymethylcytosine.
Nucleic acids research
Mar 18, 2019
Since the discovery of 5-hydroxymethylcytosine (5hmC) as a prominent DNA modification found in mammalian genomes, an emergent question has been what role this mark plays in gene regulation. 5hmC is hypothesized to function as an intermediate in the d...
The use of experimental design for the development of a capillary zone electrophoresis method for the quantitation of captopril.
Die Pharmazie
Sep 1, 2017
A capillary zone electrophoresis (CZE) method for the quantitation of captopril (CPT) using UV detection was developed. Influence of electrolyte concentration and system variables on electrophoretic separation was evaluated and a central composite de...
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