AIMC Topic: Pancreas, Artificial
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Research Gaps, Challenges, and Opportunities in Automated Insulin Delivery Systems.
Journal of diabetes science and technology
Jul 1, 2025
BACKGROUND: Since the discovery of the life-saving hormone insulin in 1921 by Dr Frederick Banting in 1921, there have been many critical discoveries and technical breakthroughs that have enabled people living with type 1 diabetes (T1D) to live longe...
A safe-enhanced fully closed-loop artificial pancreas controller based on deep reinforcement learning.
PloS one
Jan 27, 2025
Patients with type 1 diabetes and their physicians have long desired a fully closed-loop artificial pancreas (AP) system that can alleviate the burden of blood glucose regulation. Although deep reinforcement learning (DRL) methods theoretically enabl...
Hybrid Control Policy for Artificial Pancreas via Ensemble Deep Reinforcement Learning.
IEEE transactions on bio-medical engineering
Jan 15, 2025
OBJECTIVE: The artificial pancreas (AP) shows promise for closed-loop glucose control in type 1 diabetes mellitus (T1DM). However, designing effective control policies for the AP remains challenging due to complex physiological processes, delayed ins...
Parental perspectives following the implementation of advanced hybrid closed-loop therapy in children and adolescents with type 1 diabetes and elevated glycaemia.
Diabetic medicine : a journal of the British Diabetic Association
Nov 25, 2024
AIMS: To identify from a parental perspective facilitators and barriers of effective implementation of advanced hybrid closed-loop (AHCL) therapy in children and adolescents with type 1 diabetes (T1D) with elevated glycaemia.
A Deep Learning Framework for Automatic Meal Detection and Estimation in Artificial Pancreas Systems.
Sensors (Basel, Switzerland)
Jan 8, 2022
Current artificial pancreas (AP) systems are hybrid closed-loop systems that require manual meal announcements to manage postprandial glucose control effectively. This poses a cognitive burden and challenge to users with T1D since this relies on freq...
Data-Driven Robust Control for a Closed-Loop Artificial Pancreas.
IEEE/ACM transactions on computational biology and bioinformatics
Dec 8, 2020
We present a fully closed-loop design for an artificial pancreas (AP) that regulates the delivery of insulin for the control of Type I diabetes. Our AP controller operates in a fully automated fashion, without requiring any manual interaction with th...
Artificial Intelligence in Decision Support Systems for Type 1 Diabetes.
Sensors (Basel, Switzerland)
Jun 5, 2020
Type 1 diabetes (T1D) is a chronic health condition resulting from pancreatic beta cell dysfunction and insulin depletion. While automated insulin delivery systems are now available, many people choose to manage insulin delivery manually through insu...
Glucose outcomes of a learning-type artificial pancreas with an unannounced meal in type 1 diabetes.
Computer methods and programs in biomedicine
Feb 26, 2020
BACKGROUND AND OBJECTIVES: Glycemic control with unannounced meals is the major challenge for artificial pancreas. In this study, we described the performance and safety of learning-type model predictive control (L-MPC) for artificial pancreas challe...
Glycemic-aware metrics and oversampling techniques for predicting blood glucose levels using machine learning.
PloS one
Dec 2, 2019
Techniques using machine learning for short term blood glucose level prediction in patients with Type 1 Diabetes are investigated. This problem is significant for the development of effective artificial pancreas technology so accurate alerts (e.g. hy...
Prediction of Hypoglycemia During Aerobic Exercise in Adults With Type 1 Diabetes.
Journal of diabetes science and technology
Jan 17, 2019
BACKGROUND: Fear of exercise related hypoglycemia is a major reason why people with type 1 diabetes (T1D) do not exercise. There is no validated prediction algorithm that can predict hypoglycemia at the start of aerobic exercise.
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