AIMC Topic: Phosphofructokinase-2

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Targeting PFKFB3 to restore glucose metabolism in acute pancreatitis via nanovesicle delivery.

Molecular medicine (Cambridge, Mass.)
BACKGROUND: Acute pancreatitis (AP) is a severe inflammatory disease frequently accompanied by disturbances in glucose metabolism, which further complicate the disease prognosis. This study aims to explore the role of PFKFB3, a key glycolytic enzyme,...

Machine learning reveals glycolytic key gene in gastric cancer prognosis.

Scientific reports
Glycolysis is recognized as a central metabolic pathway in the neoplastic evolution of gastric cancer, exerting profound effects on the tumor microenvironment and the neoplastic growth trajectory. However, the identification of key glycolytic genes t...