Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
39742621
Phosphodiesterase type 5 inhibitors (PDE5is), primarily used for the treatment of erectile dysfunction, have been severely misused in recent years, posing a threat to public health and safety. This study developed a method that combines Surface-enhan...
Multiple sclerosis (MS) is a severe brain disease that permanently destroys brain cells, impacting vision, balance, muscle control, and daily activity. This research employs a weighted combination of deep neural networks and optimization techniques f...
Brain tumors are among the most dangerous, due to their location in the organ that governs all life processes. Moreover, the high differentiation of these poses a challenge in diagnostics. Therefore, this study focused on the chemical differentiation...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
39733534
The main objective of this study was to evaluate the potential of near infrared (NIR) spectroscopy and machine learning in detecting microplastics (MPs) in chicken feed. The application of machine learning techniques in building optimal classificatio...
Coronary artery disease represents a formidable health threat to middle-aged and elderly populations worldwide. This research introduces an advanced BP neural network algorithm, EPSOSA-BP, which integrates particle swarm optimization, simulated annea...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
39729705
The non-invasive detection of crack/cocaine and other bioactive compounds from its pyrolysis in saliva can provide an alternative for drug analysis in forensic toxicology. Therefore, a highly sensitive, fast, reagent-free, and sustainable approach wi...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
39793252
Surface-enhanced Raman scattering (SERS) show great potential for rapid and highly sensitive detection of trace amounts of contamination from the environment in the surface aquatic ecosystem. The widespread use of antibiotics has resulted in serious ...
In early-stage development of therapeutic monoclonal antibodies, assessment of the viability and ease of their purification typically requires extensive experimentation. However, the work required for upstream protein expression and downstream purifi...
BACKGROUND: Mild cognitive impairment (MCI) is recognized as a condition that may increase the risk of developing Alzheimer's disease (AD). Understanding the neural correlates of MCI is crucial for elucidating its pathophysiology and developing effec...
Postpartum depression (PPD) poses significant risks to maternal and infant health, yet proteomic analyses of PPD-risk women remain limited. This study analyzed plasma samples from 30 healthy postpartum women and 30 PPD-risk women using mass spectrome...