AIMC Topic: Relative Biological Effectiveness

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Deep learning-based synthetic dose-weighted LET map generation for intensity modulated proton therapy.

Physics in medicine and biology Jan 5, 2024
The advantage of proton therapy as compared to photon therapy stems from the Bragg peak effect, which allows protons to deposit most of their energy directly at the tumor while sparing healthy tissue. However, even with such benefits, proton therapy ...
Deep Learning Radiotherapy Planning, Computer-Assisted Monte Carlo Method Proton Therapy Protons Linear Energy Transfer Relative Biological Effectiveness
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An artificial intelligence-based model for cell killing prediction: development, validation and explainability analysis of the ANAKIN model.

Physics in medicine and biology Apr 10, 2023
The present work develops ANAKIN: an. ANAKIN is trained and tested over 513 cell survival experiments with different types of radiation contained in the publicly available PIDE database. We show how ANAKIN accurately predicts several relevant biologi...
Artificial Intelligence Cell Line Cell Death Radiobiology Relative Biological Effectiveness
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Moving Forward in the Next Decade: Radiation Oncology Sciences for Patient-Centered Cancer Care.

JNCI cancer spectrum May 17, 2021
In a time of rapid advances in science and technology, the opportunities for radiation oncology are undergoing transformational change. The linkage between and understanding of the physical dose and induced biological perturbations are opening entire...
Humans Artificial Intelligence Research Neoplasms Big Data Radiation Oncology Patient-Centered Care Radiopharmaceuticals Photochemotherapy Clinical Trials as Topic Radiotherapy Hyperthermia, Induced Radiation Tolerance Radiobiology Research Support as Topic Neutron Capture Therapy Relative Biological Effectiveness
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