AIMC Topic: Ribonucleases

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Multi-omics identification of RNASE6 as an immune regulatory RNA-binding protein associated with melanoma metastasis.

Autoimmunity
BACKGROUND: Cutaneous melanoma is a highly invasive tumor. It enhances metastasis and resistance to immunotherapy immunosuppressive mechanisms. Understanding RNA-binding proteins (RBPs) in melanoma's immune alterations is limited. This study explore...

Echo2Pheno: a deep-learning application to uncover echocardiographic phenotypes in conscious mice.

Mammalian genome : official journal of the International Mammalian Genome Society
Echocardiography, a rapid and cost-effective imaging technique, assesses cardiac function and structure. Despite its popularity in cardiovascular medicine and clinical research, image-derived phenotypic measurements are manually performed, requiring ...

Changes in brain ribonuclease (BRB) messenger RNA in granulosa cells (GCs) of dominant vs subordinate ovarian follicles of cattle and the regulation of BRB gene expression in bovine GCs.

Domestic animal endocrinology
Brain ribonuclease (BRB) is a member of the ribonuclease A superfamily that is constitutively expressed in a range of tissues and is the functional homolog of human ribonuclease 1. This study was designed to characterize BRB gene expression in granul...