Recent advances in computing power triggered the use of artificial intelligence in image analysis in life sciences. To train these algorithms, a large enough set of certified labeled data is required. The trained neural network is then capable of pro...
Blood-invasive fungal infections can cause the death of patients, while diagnosis of fungal infections is challenging. A high-speed microscopy detection system was constructed that included a microfluidic system, a microscope connected to a high-sp...
mRNA levels of all genes in a genome is a critical piece of information defining the overall state of the cell in a given environmental condition. Being able to reconstruct such condition-specific expression in fungal genomes is particularly importan...
During starvation in the yeast vacuolar vesicles fuse and lipid droplets (LDs) can become internalized into the vacuole in an autophagic process named lipophagy. There is a lack of tools to quantitatively assess starvation-induced vacuole fusion and...
IEEE/ACM transactions on computational biology and bioinformatics
Oct 9, 2023
It has been demonstrated that RNA modifications play essential roles in multiple biological processes. Accurate identification of RNA modifications in the transcriptome is critical for providing insights into the biological functions and mechanisms. ...
IEEE/ACM transactions on computational biology and bioinformatics
Oct 9, 2023
The knowledge of protein-protein interaction (PPI) helps us to understand proteins' functions, the causes and growth of several diseases, and can aid in designing new drugs. The majority of existing PPI research has relied mainly on sequence-based ap...
Artificial intelligence (AI) has become a focal point across a multitude of societal sectors, with science not being an exception. Particularly in the life sciences, imaging flow cytometry has increasingly integrated AI for automated management and c...
Every year biotechnology labs generate a combined total of ∼5.5 million tons of plastic waste. As the global bioeconomy expands, biofoundries will inevitably increase plastic consumption in-step with synthetic biology scaling. Decontamination and reu...
In-flow phase-contrast tomography provides a 3D refractive index of label-free cells in cytometry systems. Its major limitation, as with any quantitative phase imaging approach, is the lack of specificity compared to fluorescence microscopy, thus res...
Statistical applications in genetics and molecular biology
Sep 4, 2023
Proteins are the building blocks of all living things. Protein function must be ascertained if the molecular mechanism of life is to be understood. While CNN is good at capturing short-term relationships, GRU and LSTM can capture long-term dependenci...
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