AI Medical Compendium Topic

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Tomography, X-Ray

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Deep learning model calibration for improving performance in class-imbalanced medical image classification tasks.

PloS one
In medical image classification tasks, it is common to find that the number of normal samples far exceeds the number of abnormal samples. In such class-imbalanced situations, reliable training of deep neural networks continues to be a major challenge...

3D surface reconstruction of cellular cryo-soft X-ray microscopy tomograms using semisupervised deep learning.

Proceedings of the National Academy of Sciences of the United States of America
Cryo-soft X-ray tomography (cryo-SXT) is a powerful method to investigate the ultrastructure of cells, offering resolution in the tens of nanometer range and strong contrast for membranous structures without requiring labeling or chemical fixation. T...

Automated quantification of vacuole fusion and lipophagy in from fluorescence and cryo-soft X-ray microscopy data using deep learning.

Autophagy
During starvation in the yeast vacuolar vesicles fuse and lipid droplets (LDs) can become internalized into the vacuole in an autophagic process named lipophagy. There is a lack of tools to quantitatively assess starvation-induced vacuole fusion and...