AIMC Topic: Tomography, X-Ray

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Automated quantification of vacuole fusion and lipophagy in from fluorescence and cryo-soft X-ray microscopy data using deep learning.

Autophagy Oct 31, 2023
During starvation in the yeast vacuolar vesicles fuse and lipid droplets (LDs) can become internalized into the vacuole in an autophagic process named lipophagy. There is a lack of tools to quantitatively assess starvation-induced vacuole fusion and...
Deep Learning Autophagy Microscopy, Fluorescence Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Lipid Droplets Vacuoles Tomography, X-Ray
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3D surface reconstruction of cellular cryo-soft X-ray microscopy tomograms using semisupervised deep learning.

Proceedings of the National Academy of Sciences of the United States of America Jun 5, 2023
Cryo-soft X-ray tomography (cryo-SXT) is a powerful method to investigate the ultrastructure of cells, offering resolution in the tens of nanometer range and strong contrast for membranous structures without requiring labeling or chemical fixation. T...
Animals Deep Learning Image Processing, Computer-Assisted Microscopy, Fluorescence Mammals Cryoelectron Microscopy X-Rays Tomography, X-Ray
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Deep learning model calibration for improving performance in class-imbalanced medical image classification tasks.

PloS one Jan 27, 2022
In medical image classification tasks, it is common to find that the number of normal samples far exceeds the number of abnormal samples. In such class-imbalanced situations, reliable training of deep neural networks continues to be a major challenge...
Humans Deep Learning Models, Theoretical Fundus Oculi Calibration Tomography, X-Ray
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Total radius BMD correlates with the hip and lumbar spine BMD among post-menopausal patients with fragility wrist fracture in a machine learning model.

Archives of osteoporosis May 14, 2025
UNLABELLED: Osteoporosis screening should be systematic in the group of over 50-year-old females with a radius fracture. We tested a phantom combined with machine learning model and studied osteoporosis-related variables. This machine learning model ...
Humans Machine Learning Bone Density Osteoporosis Female Aged Middle Aged Mass Screening Lumbar Vertebrae Postmenopause Bone Diseases, Metabolic Absorptiometry, Photon Radius Radius Fractures Phantoms, Imaging Hip Finland Osteoporosis, Postmenopausal Osteoporotic Fractures Wrist Injuries Tomography, X-Ray Wrist Fractures
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