Sequence Deletion

Prediction of sgRNA on-target activity in bacteria by deep learning.

BMC bioinformatics 31651233

BACKGROUND: One of the main challenges for the CRISPR-Cas9 system is selecting optimal single-guide RNAs (sgRNAs). Recently, deep learning has enhanced sgRNA prediction in eukaryotes. However, the prokaryotic chromatin structure is different from euk...

Bacteria CRISPR-Cas Systems Deep Learning Gene Editing Neural Networks, Computer RNA, Guide, CRISPR-Cas Systems Sequence Deletion

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DeepSV: accurate calling of genomic deletions from high-throughput sequencing data using deep convolutional neural network.

BMC bioinformatics 31830921

BACKGROUND: Calling genetic variations from sequence reads is an important problem in genomics. There are many existing methods for calling various types of variations. Recently, Google developed a method for calling single nucleotide polymorphisms (...

Base Sequence Chromosomes, Human Genomics High-Throughput Nucleotide Sequencing Humans Machine Learning Neural Networks, Computer Sequence Deletion Software

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Comprehensive Molecular and Pathologic Evaluation of Transitional Mesothelioma Assisted by Deep Learning Approach: A Multi-Institutional Study of the International Mesothelioma Panel from the MESOPATH Reference Center.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 32165206

INTRODUCTION: Histologic subtypes of malignant pleural mesothelioma are a major prognostic indicator and decision denominator for all therapeutic strategies. In an ambiguous case, a rare transitional mesothelioma (TM) pattern may be diagnosed by path...

Deep Learning Homozygote Humans Lung Neoplasms Mesothelioma Sequence Deletion Tumor Suppressor Proteins Ubiquitin Thiolesterase

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Editorial for "Preoperative Discrimination of CDKN2A/B Homozygous Deletion Status in Isocitrate Dehydrogenase-Mutant Astrocytoma: A Deep Learning-Based Radiomics Model Using MRI".

Journal of magnetic resonance imaging : JMRI 37306402

Astrocytoma Brain Neoplasms Cyclin-Dependent Kinase Inhibitor p16 Deep Learning Homozygote Humans Isocitrate Dehydrogenase Magnetic Resonance Imaging Mutation Radiomics Sequence Deletion

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Preoperative Discrimination of CDKN2A/B Homozygous Deletion Status in Isocitrate Dehydrogenase-Mutant Astrocytoma: A Deep Learning-Based Radiomics Model Using MRI.

Journal of magnetic resonance imaging : JMRI 37555723

BACKGROUND: Cyclin-dependent kinase inhibitor 2A/B (CDKN2A/B) homozygous deletion has been verified as an independent and critical biomarker of negative prognosis and short survival in isocitrate dehydrogenase (IDH)-mutant astrocytoma. Therefore, non...

Astrocytoma Cyclin-Dependent Kinase Inhibitor p16 Deep Learning Homozygote Humans Isocitrate Dehydrogenase Magnetic Resonance Imaging Radiomics Retrospective Studies Sequence Deletion

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A novel MRI-based deep learning networks combined with attention mechanism for predicting CDKN2A/B homozygous deletion status in IDH-mutant astrocytoma.

European radiology 37553486

OBJECTIVES: To develop a high-accuracy MRI-based deep learning method for predicting cyclin-dependent kinase inhibitor 2A/B (CDKN2A/B) homozygous deletion status in isocitrate dehydrogenase (IDH)-mutant astrocytoma.

Astrocytoma Brain Neoplasms Cyclin-Dependent Kinase Inhibitor p16 Deep Learning Glioma Homozygote Humans Isocitrate Dehydrogenase Magnetic Resonance Imaging Mutation Sequence Deletion

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Medical Statistics Unlock the Gateway to Further Research: Using Deep Learning to Predict CDKN2A/B Homozygous Deletion in Isocitrate Dehydrogenase-Mutant Astrocytoma.

Korean journal of radiology 38016690

Astrocytoma Cyclin-Dependent Kinase Inhibitor p16 Deep Learning Homozygote Humans Isocitrate Dehydrogenase Magnetic Resonance Imaging Public Health Sequence Deletion

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Response to "Medical Statistics Unlock the Gateway to Further Research: Using Deep Learning to Predict CDKN2A/B Homozygous Deletion in Isocitrate Dehydrogenase-Mutant Astrocytoma".

Korean journal of radiology 38016689

Astrocytoma Cyclin-Dependent Kinase Inhibitor p16 Deep Learning Homozygote Humans Isocitrate Dehydrogenase Public Health Sequence Deletion

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Prediction of sgRNA on-target activity in bacteria by deep learning.

DeepSV: accurate calling of genomic deletions from high-throughput sequencing data using deep convolutional neural network.

Comprehensive Molecular and Pathologic Evaluation of Transitional Mesothelioma Assisted by Deep Learning Approach: A Multi-Institutional Study of the International Mesothelioma Panel from the MESOPATH Reference Center.

Editorial for "Preoperative Discrimination of CDKN2A/B Homozygous Deletion Status in Isocitrate Dehydrogenase-Mutant Astrocytoma: A Deep Learning-Based Radiomics Model Using MRI".

Preoperative Discrimination of CDKN2A/B Homozygous Deletion Status in Isocitrate Dehydrogenase-Mutant Astrocytoma: A Deep Learning-Based Radiomics Model Using MRI.

A novel MRI-based deep learning networks combined with attention mechanism for predicting CDKN2A/B homozygous deletion status in IDH-mutant astrocytoma.

Medical Statistics Unlock the Gateway to Further Research: Using Deep Learning to Predict CDKN2A/B Homozygous Deletion in Isocitrate Dehydrogenase-Mutant Astrocytoma.

Response to "Medical Statistics Unlock the Gateway to Further Research: Using Deep Learning to Predict CDKN2A/B Homozygous Deletion in Isocitrate Dehydrogenase-Mutant Astrocytoma".

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