AIMC Topic: Sodium Potassium Chloride Symporter Inhibitors

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Optimizing Loop Diuretic Treatment for Mortality Reduction in Patients With Acute Dyspnea Using a Practical Offline Reinforcement Learning Pipeline for Health Care: Retrospective Single-Center Simulation Study.

JMIR medical informatics Oct 10, 2025
BACKGROUND: Offline reinforcement learning (RL) has been increasingly applied to clinical decision-making problems. However, due to the lack of a standardized pipeline, prior work often relied on strategies that may lead to overfitted policies and in...
Humans Retrospective Studies Female Aged Adult Male Middle Aged Hospital Mortality Emergency Service, Hospital Acute Disease Dyspnea Michigan Sodium Potassium Chloride Symporter Inhibitors Reinforcement, Psychology
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Intravenous Chlorothiazide Versus Enteral Metolazone to Augment Loop Diuretic Therapy in the Intensive Care Unit.

The Annals of pharmacotherapy Dec 16, 2016
BACKGROUND: In cases of loop diuretic resistance in the intensive care unit (ICU), recommendations for a specific second-line thiazide agent are lacking.
Humans Retrospective Studies Critical Illness Intensive Care Units Female Adult Male Administration, Oral Drug Therapy, Combination Diuresis Administration, Intravenous Chlorothiazide Furosemide Metolazone Sodium Potassium Chloride Symporter Inhibitors
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