AIMC Topic: Thioredoxins
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Identification of TXN and F5 as novel diagnostic gene biomarkers of the severe asthma based on bioinformatics and machine learning analysis.
Autoimmunity
Nov 12, 2024
Asthma poses a major threat to human health. The aim of this study was to identify genetic markers of severe asthma and analyze the relationship between key genes and immune infiltration. Differentially expressed genes (DEGs) were first screened by d...
All-Atom Protein Sequence Design Based on Geometric Deep Learning.
Angewandte Chemie (International ed. in English)
Nov 4, 2024
Designing sequences for specific protein backbones is a key step in creating new functional proteins. Here, we introduce GeoSeqBuilder, a deep learning framework that integrates protein sequence generation with side chain conformation prediction to p...
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