AIMC Topic: Time-Lapse Imaging

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Application of a methodological framework for the development and multicenter validation of reliable artificial intelligence in embryo evaluation.

Reproductive biology and endocrinology : RB&E
BACKGROUND: Artificial intelligence (AI) models analyzing embryo time-lapse images have been developed to predict the likelihood of pregnancy following in vitro fertilization (IVF). However, limited research exists on methods ensuring AI consistency ...

A novel deep learning approach to identify embryo morphokinetics in multiple time lapse systems.

Scientific reports
The use of time lapse systems (TLS) in In Vitro Fertilization (IVF) labs to record developing embryos has paved the way for deep-learning based computer vision algorithms to assist embryologists in their morphokinetic evaluation. Today, most of the l...

A deep learning model for predicting blastocyst formation from cleavage-stage human embryos using time-lapse images.

Scientific reports
Efficient prediction of blastocyst formation from early-stage human embryos is imperative for improving the success rates of assisted reproductive technology (ART). Clinics transfer embryos at the blastocyst stage on Day-5 but Day-3 embryo transfer o...

Deep learning for rapid analysis of cell divisions in vivo during epithelial morphogenesis and repair.

eLife
Cell division is fundamental to all healthy tissue growth, as well as being rate-limiting in the tissue repair response to wounding and during cancer progression. However, the role that cell divisions play in tissue growth is a collective one, requir...

Can time-lapse culture combined with artificial intelligence improve ongoing pregnancy rates in fresh transfer cycles of single cleavage stage embryos?

Frontiers in endocrinology
PURPOSE: With the rapid advancement of time-lapse culture and artificial intelligence (AI) technologies for embryo screening, pregnancy rates in assisted reproductive technology (ART) have significantly improved. However, clinical pregnancy rates in ...

Deep learning large-scale drug discovery and repurposing.

Nature computational science
Large-scale drug discovery and repurposing is challenging. Identifying the mechanism of action (MOA) is crucial, yet current approaches are costly and low-throughput. Here we present an approach for MOA identification by profiling changes in mitochon...

A novel machine-learning framework based on early embryo morphokinetics identifies a feature signature associated with blastocyst development.

Journal of ovarian research
BACKGROUND: Artificial Intelligence entails the application of computer algorithms to the huge and heterogeneous amount of morphodynamic data produced by Time-Lapse Technology. In this context, Machine Learning (ML) methods were developed in order to...

Artificial intelligence in time-lapse system: advances, applications, and future perspectives in reproductive medicine.

Journal of assisted reproduction and genetics
With the rising demand for in vitro fertilization (IVF) cycles, there is a growing need for innovative techniques to optimize procedure outcomes. One such technique is time-lapse system (TLS) for embryo incubation, which minimizes environmental chang...

Embryo ranking agreement between embryologists and artificial intelligence algorithms.

F&S science
OBJECTIVE: To evaluate the degree of agreement of embryo ranking between embryologists and eight artificial intelligence (AI) algorithms.

A machine learning approach to predict cellular mechanical stresses in response to chemical perturbation.

Biophysical journal
Mechanical stresses generated at the cell-cell level and cell-substrate level have been suggested to be important in a host of physiological and pathological processes. However, the influence various chemical compounds have on the mechanical stresses...