AIMC Topic: Time-Lapse Imaging

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Embryo ranking agreement between embryologists and artificial intelligence algorithms.

F&S science
OBJECTIVE: To evaluate the degree of agreement of embryo ranking between embryologists and eight artificial intelligence (AI) algorithms.

A machine learning approach to predict cellular mechanical stresses in response to chemical perturbation.

Biophysical journal
Mechanical stresses generated at the cell-cell level and cell-substrate level have been suggested to be important in a host of physiological and pathological processes. However, the influence various chemical compounds have on the mechanical stresses...

Comparing performance between clinics of an embryo evaluation algorithm based on time-lapse images and machine learning.

Journal of assisted reproduction and genetics
PURPOSE: This article aims to assess how differences in maternal age distributions between IVF clinics affect the performance of an artificial intelligence model for embryo viability prediction and proposes a method to account for such differences.

Deep learning system for classification of ploidy status using time-lapse videos.

F&S science
OBJECTIVE: To develop a spatiotemporal model for de prediction of euploid and aneuploid embryos using time-lapse videos from 10-115 hours after insemination (hpi).

DeepSea is an efficient deep-learning model for single-cell segmentation and tracking in time-lapse microscopy.

Cell reports methods
Time-lapse microscopy is the only method that can directly capture the dynamics and heterogeneity of fundamental cellular processes at the single-cell level with high temporal resolution. Successful application of single-cell time-lapse microscopy re...

External validation of a model for selecting day 3 embryos for transfer based upon deep learning and time-lapse imaging.

Reproductive biomedicine online
RESEARCH QUESTION: Could objective embryo assessment using iDAScore Version 2.0 perform as well as conventional morphological assessment?

Deep learning for embryo evaluation using time-lapse: a systematic review of diagnostic test accuracy.

American journal of obstetrics and gynecology
OBJECTIVE: This study aimed to investigate the accuracy of convolutional neural network models in the assessment of embryos using time-lapse monitoring.

Development and validation of deep learning based embryo selection across multiple days of transfer.

Scientific reports
This work describes the development and validation of a fully automated deep learning model, iDAScore v2.0, for the evaluation of human embryos incubated for 2, 3, and 5 or more days. We trained and evaluated the model on an extensive and diverse dat...

Human induced pluripotent stem cell formation and morphology prediction during reprogramming with time-lapse bright-field microscopy images using deep learning methods.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Human induced pluripotent stem cells (hiPSCs) represent an ideal source for patient specific cell-based regenerative medicine; however, efficiency of hiPSC formation from reprogramming cells is low. We use several deep-learn...

Association between a deep learning-based scoring system with morphokinetics and morphological alterations in human embryos.

Reproductive biomedicine online
RESEARCH QUESTION: What is the association between the deep learning-based scoring system, iDAScore, and biological events during the pre-implantation period?