Topiramate

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Advancing toward precision migraine treatment: Predicting responses to preventive medications with machine learning models based on patient and migraine features.

Headache Aug 23, 2024
OBJECTIVE: To develop machine learning models using patient and migraine features that can predict treatment responses to commonly used migraine preventive medications.
Humans Machine Learning Precision Medicine Female Adult Male Middle Aged Cohort Studies Treatment Outcome Migraine Disorders Topiramate Adrenergic beta-Antagonists Antidepressive Agents, Tricyclic
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Developing an Artificial Intelligence-Guided Signal Detection in the Food and Drug Administration Adverse Event Reporting System (FAERS): A Proof-of-Concept Study Using Galcanezumab and Simulated Data.

Drug safety Jun 10, 2023
INTRODUCTION: Time- and resource-demanding activities related to processing individual case safety reports (ICSRs) include manual procedures to evaluate individual causality with the final goal of dismissing false-positive safety signals. Eminent exp...
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Humans Artificial Intelligence Databases, Factual United States Drug-Related Side Effects and Adverse Reactions United States Food and Drug Administration Adverse Drug Reaction Reporting Systems Amitriptyline Topiramate
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Application of Counter-propagation Artificial Neural Networks in Prediction of Topiramate Concentration in Patients with Epilepsy.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques Jan 1, 2015
PURPOSE: The application of artificial neural networks in the pharmaceutical sciences is broad, ranging from drug discovery to clinical pharmacy. In this study, we explored the applicability of counter-propagation artificial neural networks (CPANNs),...
Humans Neural Networks, Computer Machine Learning Algorithms Female Adult Male Middle Aged Glomerular Filtration Rate Epilepsy Anticonvulsants Drug Interactions Chromatography, High Pressure Liquid Fructose Carbamazepine Topiramate
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