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Trefoil Factor-1

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Comprehensive multi-omics analysis identifies chromatin regulator-related signatures and TFF1 as a therapeutic target in lung adenocarcinoma through a 429-combination machine learning approach.

Frontiers in immunology 39539551
INTRODUCTION: Lung cancer is a leading cause of cancer-related deaths, with its incidence continuing to rise. Chromatin remodeling, a crucial process in gene expression regulation, plays a significant role in the development and progression of malign...
Adenocarcinoma of Lung Animals Apoptosis Biomarkers, Tumor Cell Line, Tumor Cell Proliferation Chromatin Female Gene Expression Regulation, Neoplastic Humans Lung Neoplasms Machine Learning Mice Multiomics Prognosis Trefoil Factor-1 Tumor Microenvironment Xenograft Model Antitumor Assays
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