Methods in molecular biology (Clifton, N.J.)
Jan 1, 2017
The Protein Ontology (PRO) is the reference ontology for proteins in the Open Biomedical Ontologies (OBO) foundry and consists of three sub-ontologies representing protein classes of homologous genes, proteoforms (e.g., splice isoforms, sequence vari...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2017
Src homology 2 (SH2) domain is an important subclass of modular protein domains that plays an indispensable role in several biological processes in eukaryotes. SH2 domains specifically bind to the phosphotyrosine residue of their binding peptides to ...
Knowledge of the subcellular location (SCL) of viral proteins in the host cell is important for understanding their function in depth. Therefore, we have developed "MSLVP", a two-tier prediction algorithm for predicting multiple SCLs of viral protein...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2016
The use of controlled, structured vocabularies (ontologies) has become a critical tool for scientists in the post-genomic era of massive datasets. Adoption and integration of common vocabularies and annotation practices enables cross-species comparat...
Studies in health technology and informatics
Jan 1, 2015
Many people use the Internet as one of the primary sources of health information. This is due to the high volume and easy access of freely available information regarding diseases, diagnoses and treatments. However, users may find it difficult to ret...
Studies in health technology and informatics
Jan 1, 2015
Patients with chronic diseases undergo numerous in- and outpatient treatment periods, and therefore many documents accumulate in their electronic records. We report on an on-going project focussing on the semantic enrichment of medical texts, in orde...
Studies in health technology and informatics
Jan 1, 2015
Health-related Web sites have become a primary resource to search for information on diseases, diagnoses or treatment options. Various Web sites offer a great variety of such information. However, lay people might have difficulties to assess whether ...
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