Introduction: Reliable estimation of mortality among critically ill patients is crucial for guiding clinical decisions and optimizing ICU performance. Traditional scoring systems such as APACHE, SOFA, and SAPS are commonly applied, though their predi... read more
Background and Aims: Pragmatic clinical trials are designed to assess interventions in real-world settings, and their broad inclusion criteria and clinical variability create valuable opportunities for exploring heterogeneity of treatment effects. In... read more
Background: Deep learning algorithms for tuberculosis (TB) screening frequently achieve radiologist-level performance during internal evaluation, yet their reliability often degrades when deployed to populations differing from the training domain. Su... read more
Introduction: Tacrolimus remains central to liver transplantation, yet its narrow therapeutic index and pharmacokinetic variability are associated with increased risk of post-transplant diabetes mellitus (PTDM). While polymorphisms in metabolizing en... read more
Public health policies increasingly rely on the use of complex and large datasets containing heterogeneous, multimodal data that require advanced analytical methods to extract meaningful insights and support evidence-based decision-making. Essential ... read more
Objective.Large vessel occlusion (LVO) stroke presents a major challenge in clinical practice due to the potential for poor outcomes with delayed treatment. Treatment for LVO involves highly specialized care, in particular endovascular thrombectomy, ... read more
AIMS: HER2/neu gene is amplified in 15%-20% of invasive breast cancers (IBCs), serving as critical prognostic and predictive marker. HER2-targeted therapies have improved outcomes for HER2-positive patients, highlighting the importance of accurate as... read more
Food waste is a global concern, partially caused by destructive testing and inaccurate visual inspections that misclassify quality. This study developed a machine learning-assisted handheld Raman spectroscopy for non-destructive classification of avo... read more
Cis-regulatory elements (CREs) play a crucial role in regulating gene expression by controlling transcription, making the understanding and design of these elements essential for the advancement of biology. Traditional approaches often rely on empiri... read more
The limitations of traditional pyrolysis technologies of recovered carbon fiber included long processing time, low efficiency, and unclear links between process parameters and performance. Moreover, pyrolysis alone formed residual coke on carbon fibe... read more
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