As humans embark on longer and deeper missions into space, it is crucial to understand how spaceflight impacts the immune system. Decades of discoveries, bolstered by recent multiomic analyses, have identified key immune processes that are affected b... read more
Acute occlusal interference may induce chronic masticatory myalgia in some individuals. The potential factors and underlying mechanisms that predispose one to occlusion-related masticatory myalgia remain unclear. Anxiety has been shown to facilitate ... read more
International journal of environmental health research
Oct 16, 2025
Traditional risk factor screening for breast cancer focuses on reproductive and family history. However, an increasing number of young patients without these risk factors have been diagnosed with breast cancer. This study employed an exploratory desi... read more
Direct observation is a process central to behavior science, but its implementation may be challenging in some contexts (e.g., classrooms, homes). One potential solution to improve the feasibility of conducting behavioral observation and measurement ... read more
Genetic and epigenetic variation in enhancers is associated with disease susceptibility; however, linking enhancers to target genes and predicting enhancer dysfunction remain challenging. We mapped enhancer-promoter interactions in human pancreas usi... read more
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Oct 16, 2025
Surface-enhanced Raman spectroscopy (SERS) is a non-destructive and highly sensitive technique widely used for analyzing complex biological samples. However, conventional SERS approaches for living cell analysis face significant challenges. In partic... read more
BACKGROUND: Depression exhibits significant heterogeneity in antidepressant treatment response. This study aimed to develop an Electroencephalography (EEG)-based machine learning model integrating multidimensional features to predict selective seroto... read more
Colonoscopy screening effectively identifies and removes polyps before they progress to colorectal cancer (CRC), but current follow-up guidelines rely primarily on histopathologic features, overlooking other important CRC risk factors. Variability in... read more
Journal of pharmaceutical and biomedical analysis
Oct 16, 2025
Accurate and rapid diagnosis of Mycoplasma pneumoniae infection is essential for reducing its significant health burden. An amplification-free CRISPR-Cas12a-mediated detection platform has been developed, incorporating a deep learning-optimized crRNA... read more
Transcranial ultrasound imaging plays an important role in the diagnosis of brain diseases and the monitoring of brain function. However, the quality of transcranial imaging is often impaired by the intricate acoustic properties of the skull. Accurat... read more
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