BACKGROUND: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third most common cause of cancer-related death. Cirrhosis is a major contributing factor, accounting for over 90% of HCC cases. With the high mortality rate... read more
Antimicrobial resistance is a pressing global health threat fueled by a complex interplay of biological, social, and economic factors. Despite widespread recognition of its impact, the antimicrobial resistance crisis continues to deepen because of in... read more
Medical & biological engineering & computing
Jul 11, 2025
Trauma has become a major cause of increased morbidity and mortality worldwide. In emergency response, the classification of injuries is crucial as it helps to quickly determine the criticality of the injured, allocate rescue resources rationally, an... read more
BACKGROUND: Effective prediction of immunoglobulin A nephropathy (IgAN) progression is crucial for early intervention and management. We aimed to develop and validate distinct IgAN prediction models for clinical and research applications. read more
BACKGROUND: Spectral analysis is a model-free PET quantification technique that treats the time-space signal as an impulse response to a bolus injection. Band-pass spectral analysis, considering specific frequency ranges, enables calculation of separ... read more
PURPOSE: This study investigates the automation of MRI protocoling, a routine task in radiology, using large language models (LLMs), comparing an open-source (LLama 3.1 405B) and a proprietary model (GPT-4o) with and without retrieval-augmented gener... read more
Forensic science, medicine, and pathology
Jul 11, 2025
This study evaluated the applicability of combining Demirjian's method with machine learning algorithms to estimate the chronological age of children and adolescents from southeastern Brazil, using dental development stages as predictive variables. A... read more
Study DesignCross-Sectional.ObjectivesAdult spinal deformity (ASD) affects 68% of the elderly, with surgical intervention carrying complication rates of up to 50%. Effective patient education is essential for managing expectations, yet high patient v... read more
Lung cancer is a prevalent and lethal malignancy characterised by the uncontrolled growth of abnormal cells in lung tissues, often leading to functional impairment and metastasis. With approximately 2 million new cases and 1.8 million deaths annually... read more
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