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Adenosine Triphosphatases

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Inhibition to crucial enzymes in the lethal effects of the dinoflagellate Karenia mikimotoi on the rotifer Brachionus plicatilis.

Marine environmental research
Blooms of the dinoflagellate Karenia mikimotoi have cause great financial losses to the marine aquaculture industry. However, the toxicity mechanism of this species is still not fully known. In this study, we evaluated the short-term effects of K. mi...

Nano Random Forests to mine protein complexes and their relationships in quantitative proteomics data.

Molecular biology of the cell
Ever-increasing numbers of quantitative proteomics data sets constitute an underexploited resource for investigating protein function. Multiprotein complexes often follow consistent trends in these experiments, which could provide insights about thei...

Analysis of gene expression profiles of lung cancer subtypes with machine learning algorithms.

Biochimica et biophysica acta. Molecular basis of disease
Lung cancer is one of the most common cancer types worldwide and causes more than one million deaths annually. Lung adenocarcinoma (AC) and lung squamous cell cancer (SCC) are two major lung cancer subtypes and have different characteristics in sever...

Recursive dynamics of GspE through machine learning enabled identification of inhibitors.

Computational biology and chemistry
Type II secretion System has been increasingly recognized as a key driver of virulence in many pathogenic bacteria including Achromobacter xylosoxidans. ATPase GspE is the powerhouse of the T2SS. It powers the entire secretion process by binding with...