AIMC Topic: Agranulocytosis

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Predicting clozapine-induced adverse drug reaction biomarkers using machine learning.

Scientific reports Jul 15, 2025
Clozapine is an atypical antipsychotic used for patients with treatment-resistant schizophrenia. This drug has serious adverse drug reactions (ADRs), including the risk of severe neutropenia (agranulocytosis). Patients who could benefit from clozapin...
Humans Machine Learning Algorithms Biomarkers Female Adult Male Middle Aged Schizophrenia Drug-Related Side Effects and Adverse Reactions Clozapine Antipsychotic Agents Agranulocytosis
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Machine Learning Approach for Active Vaccine Safety Monitoring.

Journal of Korean medical science Aug 9, 2021
BACKGROUND: Vaccine safety surveillance is important because it is related to vaccine hesitancy, which affects vaccination rate. To increase confidence in vaccination, the active monitoring of vaccine adverse events is important. For effective active...
Humans Machine Learning Databases, Factual Republic of Korea Vaccination Vaccines Drug-Related Side Effects and Adverse Reactions Adverse Drug Reaction Reporting Systems Product Surveillance, Postmarketing Anaphylaxis Agranulocytosis
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