AIMC Topic: Algorithms

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Combining High-Throughput Screening and Machine Learning to Predict the Formation of Both Binary and Ternary Amorphous Solid Dispersion Formulations for Early Drug Discovery and Development.

Pharmaceutical research
OBJECTIVE: Amorphous solid dispersion (ASD) is widely utilized to enhance the solubility and bioavailability of water-insoluble drugs. However, conventional experimental approaches for ASD development are often resource-intensive and time-consuming. ...

Integrating multiple spatial transcriptomics data using community-enhanced graph contrastive learning.

PLoS computational biology
Due to the rapid development of spatial sequencing technologies, large amounts of spatial transcriptomic datasets have been generated across various technological platforms or different biological conditions (e.g., control vs. treatment). Spatial tra...

An Energy-Efficient Configurable 1-D CNN-Based Multi-Lead ECG Classification Coprocessor for Wearable Cardiac Monitoring Devices.

IEEE transactions on biomedical circuits and systems
Many electrocardiogram (ECG) processors have been widely used for cardiac monitoring. However, most of them have relatively low energy efficiency, and lack configurability in classification leads number and inference algorithm models. A multi-lead EC...

Asymmetric Adaptive Heterogeneous Network for Multi-Modality Medical Image Segmentation.

IEEE transactions on medical imaging
Existing studies of multi-modality medical image segmentation tend to aggregate all modalities without discrimination and employ multiple symmetric encoders or decoders for feature extraction and fusion. They often overlook the different contribution...

CTUSurv: A Cell-Aware Transformer-Based Network With Uncertainty for Survival Prediction Using Whole Slide Images.

IEEE transactions on medical imaging
Image-based survival prediction through deep learning techniques represents a burgeoning frontier aimed at augmenting the diagnostic capabilities of pathologists. However, directly applying existing deep learning models to survival prediction may not...

Exploring Contrastive Pre-Training for Domain Connections in Medical Image Segmentation.

IEEE transactions on medical imaging
Unsupervised domain adaptation (UDA) in medical image segmentation aims to improve the generalization of deep models by alleviating domain gaps caused by inconsistency across equipment, imaging protocols, and patient conditions. However, existing UDA...

VBVT-Net: VOI-Based VVBP-Tensor Network for High-Attenuation Artifact Suppression in Digital Breast Tomosynthesis Imaging.

IEEE transactions on medical imaging
High-attenuation (HA) artifacts may lead to obscured subtle lesions and lesion over-estimation in digital breast tomosynthesis (DBT) imaging. High-attenuation artifact suppression (HAAS) is vital for widespread DBT applications in clinic. The convent...

Tackling Modality-Heterogeneous Client Drift Holistically for Heterogeneous Multimodal Federated Learning.

IEEE transactions on medical imaging
Multimodal Federated Learning (MFL) has emerged as a collaborative paradigm for training models across decentralized devices, harnessing various data modalities to facilitate effective learning while respecting data ownership. In this realm, notably,...

DEeR: Deviation Eliminating and Noise Regulating for Privacy-Preserving Federated Low-Rank Adaptation.

IEEE transactions on medical imaging
Integrating low-rank adaptation (LoRA) with federated learning (FL) has received widespread attention recently, aiming to adapt pretrained foundation models (FMs) to downstream medical tasks via privacy-preserving decentralized training. However, owi...

PASS: Test-Time Prompting to Adapt Styles and Semantic Shapes in Medical Image Segmentation.

IEEE transactions on medical imaging
Test-time adaptation (TTA) has emerged as a promising paradigm to handle the domain shifts at test time for medical images from different institutions without using extra training data. However, existing TTA solutions for segmentation tasks suffer fr...