OBJECTIVES: To study the content variation of selegiline and its metabolites in urine, and based on actual cases, to explore the feasibility for the identification of methamphetamine abuse and selegiline use by chiral analysis.
BACKGROUND: Recent animal and human studies reveal distinct cognitive and neurobiological differences between opiate and stimulant addictions; however, our understanding of the common and specific effects of these two classes of drugs remains limited...
Arterial spin labeling (ASL) magnetic resonance imaging has been widely applied to identify cerebral blood flow (CBF) abnormalities in a number of brain disorders. To evaluate its significance in detecting methamphetamine (MA) dependence, this study ...
BACKGROUND AND AIMS: Amphetamine-type stimulants are the second-most used illicit drugs globally, yet there are no US Food and Drug Administration (FDA)-approved treatments for amphetamine-type stimulant use disorders (ATSUD). The aim of this study w...
BACKGROUND: Diffusion tensor imaging (DTI) analysis along the perivascular space (ALPS) index is currently widely employed to evaluate the neurophysiological activity in various neuropsychiatric disorders. However, there remains a scarcity of studies...
Failure to manage emotional withdrawal symptoms can exacerbate relapse to methamphetamine use. Understanding the neuro-mechanisms underlying methamphetamine overuse and the associated emotional withdrawal symptoms is crucial for developing effective ...