AIMC Topic: Glymphatic System

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Coupling analysis of diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) with abnormal cerebral blood flow in methamphetamine-dependent patients and its application in machine-learning-based classification.

Journal of affective disorders Feb 15, 2025
BACKGROUND: Diffusion tensor imaging (DTI) analysis along the perivascular space (ALPS) index is currently widely employed to evaluate the neurophysiological activity in various neuropsychiatric disorders. However, there remains a scarcity of studies...
Female Adult Male Machine Learning Brain Cerebrovascular Circulation Diffusion Tensor Imaging Glymphatic System Middle Aged Methamphetamine Amphetamine-Related Disorders Humans
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Assessment of glymphatic function and white matter integrity in children with autism using multi-parametric MRI and machine learning.

European radiology Jan 23, 2025
OBJECTIVES: To assess glymphatic function and white matter integrity in children with autism spectrum disorder (ASD) using multi-parametric MRI, combined with machine learning to evaluate ASD detection performance.
Humans Machine Learning Child Magnetic Resonance Imaging White Matter Female Diffusion Tensor Imaging Male Glymphatic System Child, Preschool Autism Spectrum Disorder Retrospective Studies
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Machine Learning-Based Perivascular Space Volumetry in Alzheimer Disease.

Investigative radiology Apr 23, 2024
OBJECTIVES: Impaired perivascular clearance has been suggested as a contributing factor to the pathogenesis of Alzheimer disease (AD). However, it remains unresolved when the anatomy of the perivascular space (PVS) is altered during AD progression. T...
Aged, 80 and over Male Disease Progression Female Aged Glymphatic System Cognitive Dysfunction Magnetic Resonance Imaging Alzheimer Disease Humans Machine Learning
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Automated grading of enlarged perivascular spaces in clinical imaging data of an acute stroke cohort using an interpretable, 3D deep learning framework.

Scientific reports Jan 17, 2022
Enlarged perivascular spaces (EPVS), specifically in stroke patients, has been shown to strongly correlate with other measures of small vessel disease and cognitive impairment at 1 year follow-up. Typical grading of EPVS is often challenging and time...
Image Interpretation, Computer-Assisted Neuroimaging Diffusion Tensor Imaging Glymphatic System Imaging, Three-Dimensional Stroke Patient Acuity Male Deep Learning Humans Retrospective Studies Female
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MRI-visible dilated perivascular spaces in healthy young adults: A twin heritability study.

Human brain mapping Sep 8, 2020
We investigated the narrow-sense heritability of MRI-visible dilated perivascular spaces (dPVS) in healthy young adult twins and nontwin siblings (138 monozygotic, 79 dizygotic twin pairs, and 133 nontwin sibling pairs; 28.7 ± 3.6 years) from the Hum...
Female Inheritance Patterns Young Adult Twins Adult Glymphatic System Male Humans Magnetic Resonance Imaging White Matter Deep Learning Retrospective Studies Neuroimaging Siblings Age Factors Basal Ganglia
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3D regression neural network for the quantification of enlarged perivascular spaces in brain MRI.

Medical image analysis Oct 26, 2018
Enlarged perivascular spaces (EPVS) in the brain are an emerging imaging marker for cerebral small vessel disease, and have been shown to be related to increased risk of various neurological diseases, including stroke and dementia. Automated quantifi...
Glymphatic System Aged Image Interpretation, Computer-Assisted Aged, 80 and over Cerebral Small Vessel Diseases Male Middle Aged Imaging, Three-Dimensional Humans Magnetic Resonance Imaging Algorithms Neural Networks, Computer Female Reproducibility of Results
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Enlarged perivascular spaces in brain MRI: Automated quantification in four regions.

NeuroImage Oct 13, 2018
Enlarged perivascular spaces (PVS) are structural brain changes visible in MRI, are common in aging, and are considered a reflection of cerebral small vessel disease. As such, assessing the burden of PVS has promise as a brain imaging marker. Visual ...
Glymphatic System Humans Deep Learning Brain Female Neuroimaging Magnetic Resonance Imaging Aged Cerebral Small Vessel Diseases Image Interpretation, Computer-Assisted Male
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