European respiratory review : an official journal of the European Respiratory Society
Aug 6, 2025
Several interstitial lung diseases (ILDs) with different aetiologies and pathogenic mechanisms may exhibit a progressive behaviour, similar to idiopathic pulmonary fibrosis, with comparable functional decline and early mortality. Progressive pulmonar...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Jun 3, 2025
Myocardial fibrosis, a hallmark of heart failure (HF), contributes to disease progression and mortality by impairing cardiac function. Despite the identification of potential anti-fibrotic molecules, there is a lack of effective pharmacological inter...
INTRODUCTION: Fibrosis can damage the normal function of many organs, such as cardiac function, for which no effective clinical therapies exist. However, traditional approaches to anti-fibrosis drug discovery have primarily focused on the final biolo...
UNLABELLED: Excessive production of extracellular matrix is a key component in the pathogenesis of Salzmann's nodular degeneration (SND). studies of drugs that suppress excessive fibroblast activity may become crucial in developing pathogenetically ...
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