AIMC Topic: Antifibrotic Agents

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A high-throughput analysis of novel anti-fibrotics in human adult cardiac fibroblasts.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Myocardial fibrosis, a hallmark of heart failure (HF), contributes to disease progression and mortality by impairing cardiac function. Despite the identification of potential anti-fibrotic molecules, there is a lack of effective pharmacological inter...

[Evaluation of the efficacy of antifibrotic drugs on cell cultures in Salzmann's nodular degeneration].

Vestnik oftalmologii
UNLABELLED: Excessive production of extracellular matrix is a key component in the pathogenesis of Salzmann's nodular degeneration (SND). studies of drugs that suppress excessive fibroblast activity may become crucial in developing pathogenetically ...