AIMC Topic: Biocompatible Materials

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Biomaterials for CNS disorders: a review of development from traditional methods to AI-assisted optimization.

Journal of materials science. Materials in medicine
Treating neurodegenerative and traumatic brain disorders is profoundly challenging due to factors like permanent tissue loss and the restrictive nature of the Blood-Brain Barrier (BBB), which limits drug delivery to the brain. Biomaterials offer a pr...

Machine learning guided process optimization and sustainable valorization of coconut biochar filled PLA biocomposites.

Scientific reports
This study focuses on the valorization of coconut shell biochar (CCB) as a sustainable reinforcement in polylactic acid (PLA) biocomposites, targeting enhanced mechanical performance. PLA/CCB composites were fabricated by varying injection molding pa...

Green nanofiber biocomposites for drug delivery: A sustainable approach to advanced pharmaceutical systems.

International journal of pharmaceutics
The advancement of sustainable and biocompatible materials has opened new avenues in drug delivery systems, especially through the integration of plant-based nanofiber biocomposites. These materials, derived from renewable sources such as cellulose, ...

Recent Advances in Diagnostic Strategies and Nanotechnology-Based Therapies for Ovarian Cancer Treatment.

ACS applied bio materials
Ovarian cancer is a global silent killer in women and is the second most common cause of gynecologic cancer-related deaths. Despite significant research and advances in treatment, ovarian cancer treatment remains a challenge, as it is diagnosed in an...

Wearable Point-of-Care Biosensor for Biomolecular Assay in Health Monitoring.

ACS applied bio materials
Wearable biosensors represent a significant advancement in preventive health monitoring by enabling early disease detection through real-time bioanalysis. This review examines the evolution of point-of-care testing (POCT), with a focus on materials, ...

A detailed guide to melt electro-writing for tissue engineering applications.

Biofabrication
Melt electro-writing (MEW) is an advanced 3D printing technique with significant potential in tissue engineering due to its ability to create highly precise microscale structures using biocompatible materials. This review provides a comprehensive gui...

Toward Sex-Specific Biomaterials Innovation: A Perspective.

ACS biomaterials science & engineering
Sex-related differences influence key biological processes relevant to biomaterials research, including tissue regeneration, immune response, drug metabolism, and relevant diseases. Despite increasing recognition of sex as a critical biological varia...

Bioinspired multifunctional conductive hydrogel based on hydroxypropyl methyl cellulose for flexible sensors.

Carbohydrate polymers
Conductive hydrogels based on hydroxypropyl methyl cellulose (HPMC) show great potential in flexible sensors due to their low price and good biocompatibility. Nevertheless, the design of such conductive hydrogels with superior flexible deformability,...

Integrating Deep Learning and Real-Time Imaging to Visualize In Situ Self-Assembly of Self-Healing Interpenetrating Polymer Networks Formed by Protein and Polysaccharide Fibers.

ACS applied materials & interfaces
Fibrillar protein hydrogels are promising sustainable biomaterials for biomedical applications, but their practical use is often limited by insufficient mechanical strength and stability. To address these challenges, we transformed native proteins in...

Advanced biomaterials in immune modulation: The future of regenerative therapies.

International journal of pharmaceutics
Healing of tissue is a complex process controlled by immune responses in the forms of inflammatory, proliferative, and remodeling stages. Dysregulated immunity can interfere with healing and lead to fibrosis or chronic inflammation. Biomaterials engi...